A comparative study of three-dimensional printing directions: The degradation and toxicological profile of a PLA/PHA blend
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Authors
Gonzalez Ausejo, JenniferRydz, Joanna
Musioł, Marta
Sikorska, Wanda
Sobota, Michał
Włodarczyk, Jakub
Adamus, Grażyna
Janeczek, Henryk
Kwiecień, Iwona
Hercog, Anna
Johnston, Brian
Khan, Habib R.
Kannappan, Vinodh
Jones, Keith R.
Morris, Mark R.
Jiang, Gouzhan
Radecka, Iza
Kowalczuk, Marek
Issue Date
2018-04-17
Metadata
Show full item recordAbstract
The use of biobased plastics is of great importance for many applications. Blending thermoplastic polylactide (PLA) with polyhydroxyalkanoate (PHA) enables the formulation of a more mechanically powerful material and this enables tailored biodegradation properties. In this study we demonstrate the 3D printing of a PLA/PHA blend as a potential candidate for biocompatible material applications. The filament for 3D printing consisted of PHA, which contains predominantly 3-hydroxybutyrate units and a small amount of 3-hydroxyvalerate units, as revealed by multistage mass spectrometry (ESI-MSn). This research found that the properties of 3D printed species before and during abiotic degradation are dependent on printing orientation. Furthermore, the 3D printed specimens exhibited good biocompatibility with HEK293 cells, indicating real promise as biological scaffolds for tissue engineering applications.Citation
Gonzalez-Ausejo J., Rydz .J, Musioł M., Sikorska W., Sobota M., Włodarczyk J., Adamus G., Janeczek H.., Kwiecień I., Hercog A., Johnston B., Khan HR., Kannappan V., Jones KR., Morris MR., Jiang G., Radecka I., Kowalczuk M. (2018) 'A comparative study of three-dimensional printing directions: The degradation and toxicological profile of a PLA/PHA blend', Polymer Degradation and Stability, 152, pp. 191-207Publisher
ElsevierJournal
Polymer Degradation and StabilityAdditional Links
http://linkinghub.elsevier.com/retrieve/pii/S0141391018301253Type
Journal articleLanguage
enISSN
1873-2321ae974a485f413a2113503eed53cd6c53
10.1016/j.polymdegradstab.2018.04.024
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Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/