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    Quality control of herbal medicines

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    Authors
    Liang, Yi-Zeng
    Xie, Peishan
    Chan, Kelvin C.
    Issue Date
    2004
    Submitted date
    2007-02-07
    
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    Abstract
    Different chromatographic and electrophoretic techniques commonly used in the instrumental inspection of herbal medicines (HM) are first comprehensively reviewed. Chemical fingerprints obtained by chromatographic and electrophoretic techniques, especially by hyphenated chromatographies, are strongly recommended for the purpose of quality control of herbal medicines, since they might represent appropriately the "chemical integrities" of the herbal medicines and therefore be used for authentication and identification of the herbal products. Based on the conception of phytoequivalence, the chromatographic fingerprints of herbal medicines could be utilized for addressing the problem of quality control of herbal medicines. Several novel chemometric methods for evaluating the fingerprints of herbal products, such as the method based on information theory, similarity estimation, chemical pattern recognition, spectral correlative chromatogram (SCC), multivariate resolution, etc. are discussed in detail with examples, which showed that the combination of chromatographic fingerprints of herbal medicines and the chemometric evaluation might be a powerful tool for quality control of herbal products.
    Citation
    Journal of Chromatography B, 812(1-2): 53-70
    Publisher
    Elsevier
    URI
    http://hdl.handle.net/2436/9853
    DOI
    10.1016/j.jchromb.2004.08.041
    PubMed ID
    15556488
    Additional Links
    http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6X0P-4DCWC5R-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=2206b8c5c3f1ee0356d6fc4092f32d6b
    Type
    Journal article
    Language
    en
    ISSN
    1570-0232
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jchromb.2004.08.041
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