Kite, ChrisLahart, IanRandeva, Harpal S.Kyrou, IoannisBrown, James E. P.2024-01-172024-01-172024-01-09Kite, C., Lahart, I.M., Randeva, H.S., Kyrou, I. & Brown, J.E.P. (2024) The Influence of Polycystic Ovary Syndrome (PCOS) and Other Related Factors upon Health-Related Quality of Life in Women of Reproductive Age: A Case-Control Study, Women's Reproductive Health, 11 (3), pp. 644-666 DOI: 10.1080/23293691.2023.22939682329-369110.1080/23293691.2023.2293968http://hdl.handle.net/2436/625394© 2024 The authors. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1080/23293691.2023.2293968This study aimed to assess the impact of a polycystic ovary syndrome (PCOS) diagnosis and other factors on health-related quality of life (HRQoL) in women of reproductive age. Online questionnaires were completed and study groups compared. Potential causal relationships were evaluated using path analysis. Analyses revealed that a PCOS diagnosis alongside BMI had the largest effect on HRQoL. Higher levels of physical activity (PA) were not associated with greater HRQoL, and PA was not directly affected by any other outcome. However, reduced self-esteem was identified as a key factor in the promotion of physical and mental health.application/pdfenphysical activitywomen’s healthmental healthphysical healthpath analysisself-esteempolycystic ovary syndromePCOSJournal article2329-3713Women's Reproductive Health2024-01-16