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Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health
Sakellariou, Paraskevi Valente, Angelica Carrillo, Andres E Metsios, George S Nadolnik, Liliya Jamurtas, Athanasios Z Koutedakis, Yiannis Boguszewski, Cesar Andrade, Cláudia Marlise Balbinotti Svensson, Per-Arne
Sakellariou, Paraskevi
Valente, Angelica
Carrillo, Andres E
Metsios, George S
Nadolnik, Liliya
Jamurtas, Athanasios Z
Koutedakis, Yiannis
Boguszewski, Cesar
Andrade, Cláudia Marlise Balbinotti
Svensson, Per-Arne
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2016-05-11
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Abstract
Obesity constitutes a serious global health concern reaching pandemic prevalence rates. The existence of functional brown adipose tissue (BAT) in adult humans has provoked intense research interest in the role of this metabolically active tissue in whole-body energy balance and body weight regulation. A number of environmental, physiological, pathological, and pharmacological stimuli have been proposed to induce BAT-mediated thermogenesis and functional thermogenic BAT-like activity in white adipose tissue (WAT), opening new avenues for therapeutic strategies based on enhancing the number of beige adipocytes in WAT.
Citation
Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health. 2016, 93:21-6 Med. Hypotheses
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Research Unit
PubMed ID
27372851
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Journal article
Language
en
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ISSN
0306-9877