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Quality control of herbal medicines
Liang, Yi-Zeng Xie, Peishan Chan, Kelvin C.
Liang, Yi-Zeng
Xie, Peishan
Chan, Kelvin C.
Editors
Other contributors
Affiliation
Epub Date
Issue Date
2004
Submitted date
2007-02-07
Alternative
Abstract
Different chromatographic and electrophoretic techniques commonly used in the instrumental inspection of herbal medicines (HM) are first comprehensively reviewed. Chemical fingerprints obtained by chromatographic and electrophoretic techniques, especially by hyphenated chromatographies, are strongly recommended for the purpose of quality control of herbal medicines, since they might represent appropriately the "chemical integrities" of the herbal medicines and therefore be used for authentication and identification of the herbal products. Based on the conception of phytoequivalence, the chromatographic fingerprints of herbal medicines could be utilized for addressing the problem of quality control of herbal medicines. Several novel chemometric methods for evaluating the fingerprints of herbal products, such as the method based on information theory, similarity estimation, chemical pattern recognition, spectral correlative chromatogram (SCC), multivariate resolution, etc. are discussed in detail with examples, which showed that the combination of chromatographic fingerprints of herbal medicines and the chemometric evaluation might be a powerful tool for quality control of herbal products.
Citation
Journal of Chromatography B, 812(1-2): 53-70
Publisher
Journal
Research Unit
PubMed ID
15556488
PubMed Central ID
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Type
Journal article
Language
en
Description
Series/Report no.
ISSN
1570-0232