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Women's views on autologous cell-based therapy for post-obstetric incontinence
Wright, Bernice Emmanuel, Anton Athanasakos, Eleni Parmar, Nina Parker, Georgina Green, Belinda Tailby, Emma Chandler, Heidi Cushnie, Julyette Pembroke, June
Wright, Bernice
Emmanuel, Anton
Athanasakos, Eleni
Parmar, Nina
Parker, Georgina
Green, Belinda
Tailby, Emma
Chandler, Heidi
Cushnie, Julyette
Pembroke, June
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2016-02
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Abstract
Aim: Fecal and urinary incontinence are devastating consequences of obstetric-related perineal injury. The aim of the present study is to determine acceptability to parous women of autologous cell-based therapy for fecal and urinary incontinence that arises due to pelvic diaphragm tearing during vaginal childbirth. Materials & methods: A multiple choice questionnaire survey was offered to 76 parous women at the Maternity Unit, University College Hospital, London, UK. Seventy completed questionnaires – response rate: 92%. Results: In total, 84% of women indicated a willingness to accept autologous cell-based therapy for obstetric injury-induced incontinence rather than surgery. Conclusion: These observational data provide an indication of likely acceptance of autologous cell-based therapies for birth injury incontinence and will help with designing new therapeutic approaches.
Citation
Wright, B., Emmanuel, A., Athanasakos, E., Parmar, N., Parker, G., Green, B., Tailby, E., Chandler, H., Cushnie, J., Pembroke, J., Saruchera, Y., Vashisht, A. and & Day, R. (2016) Women's views on autologous cell-based therapy for post-obstetric incontinence, Regenerative Medicine, 11(2), pp. 169-180.
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Journal article
Language
en
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1746-0751
EISSN
1746-076X
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The project was supported by grants from the UK Medical Research Council (MR/L002752/1), The Sir Halley Stewart Trust, The Henry Smith Charity, and the UCL Grand Challenge Studentship Scheme. The research was undertaken at UCL/UCLH which receives funding from the Department of Health's NIHR as a Comprehensive Biomedical Research Centre.