Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise
Paschalis, Vassilis Nikolaidis, Michalis G. Fatouros, Ioannis Giakas, Giannis Koutedakis, Yiannis Karatzaferi, Christina Kouretas, Dimitris Jamurtas, Athanasios Z.
Paschalis, Vassilis
Nikolaidis, Michalis G.
Fatouros, Ioannis
Giakas, Giannis
Koutedakis, Yiannis
Karatzaferi, Christina
Kouretas, Dimitris
Jamurtas, Athanasios Z.
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2007
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Abstract
Background: The effect of eccentic exercise on the time-course changes in several indices of muscle damage and blood oxidative stress as examined. Materials and methods: Isometric rorque, delayed-onset muscle soreness, creatine kinase, reduced glutathione (GSH), oxidized glutathione (GSSG), thiobarbituric-acid reactive substances (TBARS), protein carbonyls, catalase, uric acid, bilirubin and total antioxidant capacity (TAC) in blood were measured pre-, 24 h, 48 h and 72 h post-exercise of knee extensors in ten females. Results: The concentration of all oxidative stress indices changed significantly in a way indicating increased oxidative stress in the blood (GSH and GSH/GSSG, decreased, whereas GSSG, TBARS, protein carbonyls, catalase, uric acid, bilirubin and TAC increased) peaking, in all but TBARS, at 48 h and returning towards baseline afterwards. Conclusion: We believe that muscle-damaging exercise should be viewedd as a different challenge compared to non-muscle-damaging exercise with regard to its effects on blood oxidative stress.
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In vivo, 21: 877-884
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Journal article
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en
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0258-851x