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Prolactin monitoring for patients on antipsychotic drugs: A narrative review of clinical relevance

Cook, Natalie
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Abstract
Hyperprolactinemia is known to be a common side effect of antipsychotic drugs. It is associated with specific symptoms and long-term complications. There are inconsistencies in the monitoring of prolactin in patients taking antipsychotic medications. It was intended to review the recent literature regarding causes, symptoms of hyperprolactinemia, monitoring guidelines about antipsychotic drug-induced hyperprolactinemia, and suggested treatment approaches. There are multiple etiologies of hyperprolactinemia, which include side effects of a wide range of medications. While it is not recommended to monitor prolactin in all patients taking antipsychotic medication routinely, there are variations of approaches based on the antipsychotic drugs and the presence of hyperprolactinemia symptoms. Observations in this narrative review based on current evidence suggest careful clinical investigation and monitoring of hyperprolactinemia in psychiatric patients.
Citation
Kar, N., Cook, N. (2025) Prolactin monitoring for patients on antipsychotic drugs: A narrative review of clinical relevance. Archives of Biological Psychiatry, 3 (1), pp. 11-18. doi: 10.25259/ABP_17_2025
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Journal article
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en
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© 2025 The Authors. Published by Scientific Scholar on behalf of Archives of Biological Psychiatry. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://archivesbiologicalpsychiatry.org/prolactin-monitoring-for-patients-on-antipsychotic-drugs-a-narrative-review-of-clinical-relevance/
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2994-4597
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