Loading...
Impact of fish consumption on all-cause mortality in older people with and without dementia: a community-based cohort study
Bakre, Aishat Chen, Anthony Tao, Xuguang Hou, Jian Yao, Yuyou Tang, James Jie Rohrmann, Sabine Ni, Jindong Hu, Zhi
Bakre, Aishat
Chen, Anthony
Tao, Xuguang
Hou, Jian
Yao, Yuyou
Tang, James Jie
Rohrmann, Sabine
Ni, Jindong
Hu, Zhi
Editors
Other contributors
Affiliation
Epub Date
Issue Date
2022-06-24
Submitted date
Subjects
Alternative
Abstract
Background: Increased fish consumption reduces the risk of dementia. However, it is unknown whether fish consumption reduced all-cause mortality in people with dementia. The purpose of the study is to investigate the association of fish consumption with all-cause mortality in older people with dementia versus those without dementia. Methods: Using a standard method of the Geriatric Mental State, we interviewed 4165 participants aged ≥ 60 years who were randomly recruited from five provinces in China during 2007–2009 to collect the baseline data of socio-demography, disease risk factors, histories of disease, and details of dietary intakes, and diagnosed dementia (n = 406). They were followed up for vital status until 2012. Results: The cohort follow-up documented 329 deaths; 61 were in participants with dementia (55.3 per 1000 person-years) and 224 were those without dementia (22.3). In all participants, the risk of all-cause mortality was reduced with fish intake at “ ≥ twice a week” (multivariate-adjusted hazard ratio 0.58, 95% CI 0.34–0.96) and at “once a week or less” (0.79, 0.53–1.18) compared to “never eat” over the past two years. In participants without baseline dementia, the corresponding HRs for all-cause mortality were 0.57 (0.33–0.98) and 0.85 (0.55–1.31), while in participants with dementia were 1.36 (0.28–6.60) and 1.05 (0.30–3.66), respectively. Conclusion: This study reveals that consumption of fish in older age reduced all-cause mortality in older people without dementia, but not in people with dementia. Fish intake should be increased in older people in general, prior to the development of dementia in the hope of preventing dementia and prolonging life.
Citation
Bakre, A.T., Chen, A., Tao, X. et al. (2022) Impact of fish consumption on all-cause mortality in older people with and without dementia: a community-based cohort study. European Journal of Nutrition 61, pp. 3785–3794. https://doi.org/10.1007/s00394-022-02887-y
Publisher
Journal
Research Unit
PubMed ID
35748921 (pubmed)
PubMed Central ID
Embedded videos
Additional Links
Type
Journal article
Language
en
Description
© 2022 The Authors. Published by Springer. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1007/s00394-022-02887-y
Series/Report no.
ISSN
1436-6207
EISSN
1436-6215
ISBN
ISMN
Gov't Doc #
Sponsors
The data collection of the five provinces’ cohort study was funded by the BUPA Foundation (Grants Nos. 45NOV06, and TBF-M09-05) and Alzheimer’s Research UK (Grant No. ART/PPG2007B/2). The data management and the final work of the manuscript were supported by the Research fund of Anhui Medical University, China (Grant No. 2021xkjT049). Professor Ruoling Chen and Dr James J Tang thank an EU H2020 MSCA Fellowship (Grant No. DEMAIRPO-799247) to investigate the risk of dementia in relation to air pollution mediated by fish intake.
Rights
Licence for published version: Creative Commons Attribution 4.0 International