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Associations of solid fuel use and ambient air pollution with estimated 10-year atherosclerotic cardiovascular disease risk
Pan, M Li, S Tu, R Li, R Liu, X Chen, Ruoling Yu, S Mao, Z Huo, W Yin, S
Pan, M
Li, S
Tu, R
Li, R
Liu, X
Chen, Ruoling
Yu, S
Mao, Z
Huo, W
Yin, S
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2021-09-09
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Abstract
Background Although exposure to ambient air pollution (AAP) increases the risk for arteriosclerotic cardiovascular disease (ASCVD), evidence on the association of solid fuel use with ASCVD and its association modified by ambient air pollution remains limited. Methods A total of 16,779 adults were derived from the Henan Rural Cohort Study. Concentrations of ambient air pollutants (PM1, PM2.5, PM10, and NO2) were estimated by a spatiotemporal model based on satellites data. Solid fuel use was assessed by a self-reported questionnaire. The associations of solid fuel use with high 10-year ASCVD risk and the modified association by exposure to air pollutants were explored using logistic regression models. Results There were positive associations of AAP exposure with high 10-year ASCVD risk among individuals with self-cooking. The joint associations between high AAP exposures and solid fuel use with high 10-year ASCVD risk were found. Compared to clean fuel user with low PM2.5 exposure, the odds ratios (ORs) and 95% confidence intervals (CIs) of high 10-year ASCVD risk was 1.25 (1.09, 1.42) for solid fuel user with low PM2.5 exposure, 1.93 (1.75, 2.12) for clean fuel user with high PM2.5 exposure, and 3.08 (2.67, 3.54) for solid fuel user with high PM2.5 exposure, respectively. Their additive effect on high 10-year ASCVD risk was observed (relative excess risk due to interaction (RERI): 0.90 (95 %CI: 0.50, 1.30), attributable proportion due to interaction (AP): 0.29 (95 %CI: 0.19, 0.40), and synergy index (SI): 1.77 (95 %CI: 1.38, 2.26)). Conclusion This study showed a synergistic effect of AAP and household air pollution reflected by solid fuel use on high 10-year ASCVD risk, suggesting that reducing solid cooking fuels and controlling air pollution may have a joint effect on public health improvement.
Citation
Pan, M., Li, S., Tu, R. et al. (2021) Associations of solid fuel use and ambient air pollution with estimated 10-year atherosclerotic cardiovascular disease risk. Environment International, 157, 106865.
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PubMed ID
34509046 (pubmed)
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Journal article
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en
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© 2021 The Authors. Published by Elsevier. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1016/j.envint.2021.106865
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0160-4120
EISSN
1873-6750
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This research was supported by the Foundation of National Key Program of Research and Development of China (Grant NO: 2016YFC0900803), National Natural Science Foundation of China (Grant NO: U1404814, 81573243, 81602925), Henan Natural Science Foundation of China (Grant NO: 182300410293), Science and Technology Foundation for Innovation Talent of Henan Province (Grant NO: 164100510021), Science and Technology Innovation Talents Support Plan of Henan Province Colleges and Universities (Grant NO: 14HASTIT035), High-level Personnel Special Support Project of Zhengzhou University (Grant NO: ZDGD13001).