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Kikuchi-Fujimoto disease, simultaneously diagnosed with systemic lupus erythematosus in an Arabic female: an agonizing combination
Gouda, Wesam Alsaqabi, Faisal Almurshed, Maryam Mostafa, Ashraf A. Albasri, Anwar Negm, Ahmed Kamal, Mohamed
Gouda, Wesam
Alsaqabi, Faisal
Almurshed, Maryam
Mostafa, Ashraf A.
Albasri, Anwar
Negm, Ahmed
Kamal, Mohamed
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Epub Date
Issue Date
2024-05-07
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Abstract
Kikuchi–Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, benign condition affecting young Oriental-Asian females. It is characterized by fever and tender cervical lymphadenopathy with an unclear aetiology, and in most longitudinal reviews, KFD occurs before systemic lupus erythematosus (SLE). Herein, the case of a 28-year-old Kuwaiti female without any relevant past medical history, who was simultaneously diagnosed with KFD and SLE following an Ebstein–Barr virus infection, is reported. The patient was treated with oral prednisolone, hydroxychloroquine, cyclosporin, and belimumab and her response was clinically and biochemically favourable. Although KFD is prevalent in Asian populations, it may affect all races. Early diagnosis of KFD is difficult, particularly when simultaneously diagnosed with SLE, but crucial to preventing inappropriate therapy. Clinicians need to know about this rare disease, especially when patients present with fever and swollen lymph nodes, due to a risk of misdiagnosis with tuberculosis or lymphoma, as these are more often thought to be the cause of such symptoms.
Citation
Gouda, W., Alsaqabi, F., Almurshed, M., Mostafa, A.A., Albasri, A., Negm, A., Islam, M.A. and Kamal, M. (2024) Kikuchi-Fujimoto disease, simultaneously diagnosed with systemic lupus erythematosus in an Arabic female: an agonizing combination. Journal of International Medical Research, 52(5), pp. 1-8.
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Research Unit
PubMed ID
38713457 (pubmed)
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Journal article
Language
en
Description
© 2024 The Authors. Published by SAGE. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1177/03000605241248884
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ISSN
0300-0605
EISSN
1473-2300
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Licence for published version: Creative Commons Attribution-NonCommercial 4.0 International