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3D printing customised stiffness-matched meta-biomaterial with near-zero auxeticity for load-bearing tissue repair
Arjunan, Arun Singh, Manpreet
Arjunan, Arun
Singh, Manpreet
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2023-06-24
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Abstract
The evolution of meta-biomaterials has opened up exciting new opportunities for mass personalisation of biomedical devices. This research paper details the development of a CoCrMo meta-biomaterial structure that facilitates personalised stiffness-matching while also exhibiting near-zero auxeticity. Using laser powder bed fusion, the porous architecture of the meta-biomaterial was characterised, showing potential for near-zero Poisson’s ratio. The study also introduces a novel surrogate model that can predict the porosity (φ), yield strength (σy), elastic modulus (E), and negative Poisson’s ratio ( - υ) of the meta-biomaterial, which was achieved through prototype testing and numerical modelling. The model was then used to inform a multi-criteria desirability objective, revealing an optimum near-zero - υ of - 0.037, with a targeted stiffness of 17.21 GPa. Parametric analysis of the meta-biomaterial showed that it exhibited - υ, φ, σy and E values ranging from - 0.02 to -0.08, 73.63–81.38%, 41–64 MPa, and 9.46–20.6 GPa, respectively. In this study, a surrogate model was developed for the purpose of generating personalised scenarios for the production of bone scaffolds. By utilising this model, it was possible to achieve near-zero - υ and targeted stiffness personalisation. This breakthrough has significant implications for the field of bone tissue engineering and could pave the way for improved patient outcomes. The presented methodology is a powerful tool for the development of biomaterials and biomedical devices that can be 3D printed on demand for load-bearing tissue reconstruction. It has the potential to facilitate the creation of highly tailored and effective treatments for various conditions and injuries, ultimately enhancing patient outcomes.
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Wanniarachchi, C.T., Arjunan, A., Baroutaji, A. and Singh, M. (2023) 3D printing customised stiffness-matched meta-biomaterial with near-zero auxeticity for load-bearing tissue repair. Bioprinting, 33, e00292.
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Journal article
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en
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© 2023 The Authors. Published by Elsevier. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1016/j.bprint.2023.e00292
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2405-8866