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Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry

Yates, Sally A
; 
Dempster, Nicola M
; 
Murphy, Mark F
; 
Moore, Sharon A
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Yates, Sally A
 Dempster, Nicola M
 Murphy, Mark F
 Moore, Sharon A
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2017-04-16
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Abstract
The lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.
Citation
Yates, SA., Dempster, NM., Murphy, MF and Moore, SA. (2017) 'Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry'. Rapid Communications In Mass Spectrometry. 31 (9) pp. 762-770
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Wiley
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Rapid Communications In Mass Spectrometry
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http://hdl.handle.net/2436/621014
DOI
10.1002/rcm.7843
PubMed ID
28231608
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en
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Faculty of Science and Engineering