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Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry
Yates, Sally A Dempster, Nicola M Murphy, Mark F Moore, Sharon A
Yates, Sally A
Dempster, Nicola M
Murphy, Mark F
Moore, Sharon A
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2017-04-16
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S Moore RCMS 2017.pdf
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Abstract
The lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.
Citation
Yates, SA., Dempster, NM., Murphy, MF and Moore, SA. (2017) 'Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry'. Rapid Communications In Mass Spectrometry. 31 (9) pp. 762-770
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28231608
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Journal article
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en