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Effect of fat free mass on serum and plasma BDNF concentrations during exercise and recovery in healthy young men.
Gilder, M Ramsbottom, R Currie, J Sheridan, B Nevill, Alan M.
Gilder, M
Ramsbottom, R
Currie, J
Sheridan, B
Nevill, Alan M.
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2013-12-22
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Abstract
Exercise results in release of brain derived neurotrophic factor into the circulation; however, little is known about the changes in serum and plasma brain derived neurotrophic factor concentrations and factors influencing brain derived neurotrophic factor during exercise and recovery. Serum (n=23) and plasma (n=10) brain derived neurotrophic factor concentrations were measured in healthy young men at rest, during steady-rate and after exercise to determine the maximum aerobic power. A two-way analysis of variance was used to investigate brain derived neurotrophic factor levels in blood during exercise and recovery, with one between-subject factor (a median split on: age, height, body mass, fat free mass, body mass index and aerobic fitness), and one within-subject factor (time). Serum brain derived neurotrophic factor concentrations increased in response to exercise and declined rapidly in recovery. Plasma brain derived neurotrophic factor had a greater proportional increase relative to exhaustive exercise compared with serum brain derived neurotrophic factor and was slower to return to near baseline values. There was a significant group-by-time interaction indicating a greater release and faster recovery for serum brain derived neurotrophic factor in high- compared with low-fat free mass individuals.
Citation
Effect of fat free mass on serum and plasma BDNF concentrations during exercise and recovery in healthy young men. 2014, 560:137-41 Neurosci. Lett.
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Research Unit
PubMed ID
24368215
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Journal article
Language
en
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ISSN
1872-7972