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Passive heating and glycaemic control in non-diabetic and diabetic individuals: A systematic review and meta-analysis
Maley, MJ Hunt, AP Stewart, IB Faulkner, SH Minett, GM
Maley, MJ
Hunt, AP
Stewart, IB
Faulkner, SH
Minett, GM
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2019-03-22
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Abstract
© 2019 Maley et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Objective Passive heating (PH) has begun to gain research attention as an alternative therapy for car-dio-metabolic diseases. Whether PH improves glycaemic control in diabetic and non-diabetic individuals is unknown. This study aims to review and conduct a meta-analysis of published literature relating to PH and glycaemic control. Methods Electronic data sources, PubMed, Embase and Web of Science from inception to July 2018 were searched for randomised controlled trials (RCT) studying the effect of PH on glycaemic control in diabetic or non-diabetic individuals. To measure the treatment effect, standardised mean differences (SMD) with 95% confidence intervals (CI) were calculated. Results Fourteen articles were included in the meta-analysis. Following a glucose load, glucose concentration was greater during PH in non-diabetic (SMD 0.75, 95% CI 1.02 to 0.48, P < 0.001) and diabetic individuals (SMD 0.27, 95% CI 0.52 to 0.02, P = 0.030). In non-diabetic individuals, glycaemic control did not differ between PH and control only (SMD 0.11, 95% CI 0.44 to -0.22, P > 0.050) and a glucose challenge given within 24 hours post-heating (SMD 0.30, 95% CI 0.62 to -0.02, P > 0.050). Conclusion PH preceded by a glucose load results in acute glucose intolerance in non-diabetic and diabetic individuals. However, heating a non-diabetic individual without a glucose load appears not to affect glycaemic control. Likewise, a glucose challenge given within 24 hours of a single-bout of heating does not affect glucose tolerance in non-diabetic individuals. Despite the promise PH may hold, no short-term benefit to glucose tolerance is observed in non-diabetic individuals. More research is needed to elucidate whether this alternative therapy benefits diabetic individuals.
Citation
Maley M.J., Hunt A.P., Stewart I.B., Faulkner S.H., Minett G.M. (2019) Passive heating and glycaemic control in non-diabetic and diabetic individuals: A systematic review and meta-analysis. PLoS ONE 14(3): e0214223. https://doi.org/ 10.1371/journal.pone.0214223
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30901372
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Journal article
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en
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© 2019 The Authors. Published by PLOS. This is an open access article available under a Creative Commons licence.
The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1371/journal.pone.0214223
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1932-6203
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1932-6203
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Licence for published version: Creative Commons Attribution 4.0 International