Loading...
Optical coherence tomography angiography as a surrogate marker for end-organ resuscitation in sepsis: A review
Courtie, Ella Gilani, Ahmed Blanch, Richard J
Courtie, Ella
Gilani, Ahmed
Blanch, Richard J
Editors
Other contributors
Affiliation
Epub Date
Issue Date
2022-10-20
Submitted date
Alternative
Abstract
Sepsis is a severe illness which results in alterations in the end organ microvascular haemodynamics and is associated with a high risk of mortality. There is currently no real-time method of monitoring microcirculatory perfusion during sepsis. Retinal microcirculation is closely linked to cerebral perfusion and may reflect systemic vascular alterations. Retinal perfusion can be assessed using the non-invasive imaging technique of optical coherence tomography angiography (OCTA). This narrative review aims to discuss the utility of using retinal imaging and OCTA in systemic illness and sepsis. OCTA can be used as a functional, non-invasive and real-time biomarker along with other haemodynamic parameters for assessing and managing patients with sepsis.
Citation
Courtie E, Gilani A, Veenith T and Blanch RJ (2022) Optical coherence tomography angiography as a surrogate marker for end-organ resuscitation in sepsis: A review. Front. Med. 9:1023062. doi: 10.3389/fmed.2022.1023062
Publisher
Journal
Research Unit
PubMed ID
36341253 (pubmed)
PubMed Central ID
Embedded videos
Type
Journal article
Language
en
Description
© 2022 The Authors. Published by Frontiers Media SA. This is an open access article available under a Creative Commons licence.
The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.3389/fmed.2022.1023062
Series/Report no.
ISSN
2296-858X
EISSN
2296-858X
ISBN
ISMN
Gov't Doc #
Sponsors
This study was funded by the National Institute for Health Research (NIHR) Surgical Reconstruction and Microbiology Research Centre (SRMRC). TV’s research programme was supported by Medical Research Council and NIHR.
Rights
Licence for published version: Creative Commons Attribution 4.0 International