Gene encoding the collagen type I and thrombospondin receptor CD36 is located on chromosome 7q11.2.
Fernández-Ruiz, Elena ; ; Sánchez-Madrid, Francisco ; Vega, Miguel A.
Fernández-Ruiz, Elena
Sánchez-Madrid, Francisco
Vega, Miguel A.
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1993
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Abstract
The human CD36 is a member of a gene family of structurally related glycoproteins and functions as a receptor for collagen type I and thrombospondin. CD36 also binds to red blood cells infected with the human malaria parasite Plasmodium falciparum. In the present study, the CD36 gene was assigned to chromosome 7 by using the polymerase chain reaction with DNA from human-hamster somatic cell hybrids. Furthermore, the use of a CD36 genomic probe has allowed the localization of the CD36 locus to the 7q11.2 band by fluorescence in situ hybridization coupled with GTG-banding.
Citation
Genomics, 17(3): 759-761
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PubMed ID
7503937
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Journal article
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en
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ISSN
0888-7543