Risk assessment for cardiovascular disease using the Framingham risk score and Globorisk score among newly diagnosed metabolic syndrome patients

Purpose: The presence of metabolic syndrome (MetS) is linked to an increased risk of cardiovascular disease (CVD) development. In this study, CVD risk was calculated among individuals with newly diagnosed MetS using the Framingham Risk Score (FRS) and Globorisk Score. The FRS and Globorisk score are particularly relevant in predicting CVD risk as these scores include key MetS-related risk factors like blood pressure, cholesterol levels, and age. Patients and Methods: A community-based cross-sectional study was conducted at various sites in Karachi, Pakistan, from February 2022 to August 2022. Newly diagnosed cases of MetS with no physical disability, known illness, and not taking any regular medication were recruited. MetS was defined based on the definition of International Diabetes Federation. The major outcome was 10-year risk for CVD using the FRS and Globorisk Score. Results: Of 304 patients, 59.2% were classified as low risk according to FRS, while 20.4% were classified as moderate and high risk each. Using the Globorisk score, 44.6% of 224 patients were classified as low risk, 34.4% as moderate risk, and 21.0% as high risk. A moderate positive correlation was observed between the two CVD risk scores (r = 0.651, 95% CI 0.58– 0.71). Both risk scores have reported age, gender, and current smokers as significant risk factors in predicting CVD in 10-years (P < 0.05). Conclusion: The outcome of both CVD risk scores predicted moderate-to-high risk of CVD in 10-years in almost half of the newly diagnosed patients with MetS. In particular, the risk of development of CVD in 10-years in newly diagnosed MetS is higher with increasing age, in male gender, and current smokers.

Citation

Adil SO, Uddin F, Musa KI, Khan A, Shakeel A, Shafique K, Islam MA. (2023) Risk Assessment for Cardiovascular Disease Using the Framingham Risk Score and Globorisk Score Among Newly Diagnosed Metabolic Syndrome Patients. Int J Gen Med. 16 pp. 4295-4305 https://doi.org/10.2147/IJGM.S423151

PubMed ID

37753441 (pubmed)

Additional Links

https://www.dovepress.com/risk-assessment-for-cardiovascular-disease-using-the-framingham-risk-s-peer-reviewed-fulltext-article-IJGM#

Type

Journal article

Language

en

Description

© 2023 The Authors. Published by Dove Press. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.2147/IJGM.S423151

ISSN

1178-7074

EISSN

1178-7074

Rights

Licence for published version: Creative Commons Attribution-NonCommercial 4.0 International

cbn

Collections

Faculty of Science and Engineering