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The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis
Metsios, GS Moe, RH van der Esch, M van Zanten, JJCSV Fenton, SAM Koutedakis, Y Vitalis, P Kennedy, N Brodin, N Bostrom, C
Metsios, GS
Moe, RH
van der Esch, M
van Zanten, JJCSV
Fenton, SAM
Koutedakis, Y
Vitalis, P
Kennedy, N
Brodin, N
Bostrom, C
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Epub Date
Issue Date
2019-12-04
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Abstract
© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) can significantly improve patient-reported and clinical index-assessed outcomes in RA. In addition to this, engagement in exercise programmes improves, in a dose-dependent manner, the risk of developing CVD as well as CVD symptoms and outcomes. The present narrative review uses evidence from systematic reviews and meta-analyses as well as controlled trials, to synthesize the current state-of-the-art on the potential effects of aerobic and resistance exercise on CVD risk factors as well as on cardiac and vascular function and structure in people with RA. Where there is a lack of evidence in RA to explain potential mechanisms, relevant studies from the general population are also discussed and linked to RA.
Citation
Metsios, G.S., Moe, R.H., van der Esch, M. et al. (2019) The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis, Rheumatology International, https://doi.org/10.1007/s00296-019-04483-6
Publisher
Journal
Research Unit
PubMed ID
31802210
PubMed Central ID
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Type
Journal article
Language
en
Description
Series/Report no.
ISSN
0172-8172
EISSN
1437-160X