Quality control of herbal medicines

Liang, Yi-Zeng; Xie, Peishan; Chan, Kelvin C.

dc.contributor.author	Liang, Yi-Zeng
dc.contributor.author	Xie, Peishan
dc.contributor.author	Chan, Kelvin C.
dc.date.accessioned	2007-03-07T14:58:29Z
dc.date.available	2007-03-07T14:58:29Z
dc.date.issued	2004
dc.date.submitted	2007-02-07
dc.identifier.citation	Journal of Chromatography B, 812(1-2): 53-70
dc.identifier.issn	1570-0232
dc.identifier.pmid	15556488
dc.identifier.doi	10.1016/j.jchromb.2004.08.041
dc.identifier.uri	http://hdl.handle.net/2436/9853
dc.description.abstract	Different chromatographic and electrophoretic techniques commonly used in the instrumental inspection of herbal medicines (HM) are first comprehensively reviewed. Chemical fingerprints obtained by chromatographic and electrophoretic techniques, especially by hyphenated chromatographies, are strongly recommended for the purpose of quality control of herbal medicines, since they might represent appropriately the "chemical integrities" of the herbal medicines and therefore be used for authentication and identification of the herbal products. Based on the conception of phytoequivalence, the chromatographic fingerprints of herbal medicines could be utilized for addressing the problem of quality control of herbal medicines. Several novel chemometric methods for evaluating the fingerprints of herbal products, such as the method based on information theory, similarity estimation, chemical pattern recognition, spectral correlative chromatogram (SCC), multivariate resolution, etc. are discussed in detail with examples, which showed that the combination of chromatographic fingerprints of herbal medicines and the chemometric evaluation might be a powerful tool for quality control of herbal products.
dc.format.extent	584432 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en
dc.publisher	Elsevier
dc.relation.url	http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6X0P-4DCWC5R-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=2206b8c5c3f1ee0356d6fc4092f32d6b
dc.subject	Plants, Medicinal
dc.subject	Herbal medicine
dc.subject	Chromatographic fingerprints
dc.subject	Quality Control
dc.subject	Chemometrics
dc.title	Quality control of herbal medicines
dc.type	Journal article
dc.format.dig	YES
refterms.dateFOA	2018-08-20T13:52:39Z
html.description.abstract	Different chromatographic and electrophoretic techniques commonly used in the instrumental inspection of herbal medicines (HM) are first comprehensively reviewed. Chemical fingerprints obtained by chromatographic and electrophoretic techniques, especially by hyphenated chromatographies, are strongly recommended for the purpose of quality control of herbal medicines, since they might represent appropriately the "chemical integrities" of the herbal medicines and therefore be used for authentication and identification of the herbal products. Based on the conception of phytoequivalence, the chromatographic fingerprints of herbal medicines could be utilized for addressing the problem of quality control of herbal medicines. Several novel chemometric methods for evaluating the fingerprints of herbal products, such as the method based on information theory, similarity estimation, chemical pattern recognition, spectral correlative chromatogram (SCC), multivariate resolution, etc. are discussed in detail with examples, which showed that the combination of chromatographic fingerprints of herbal medicines and the chemometric evaluation might be a powerful tool for quality control of herbal products.