Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy.

Liu, Hong-xia; Sun, Su-qin; Lu, Guang-Hua; Chan, Kelvin C.

dc.contributor.author	Liu, Hong-xia
dc.contributor.author	Sun, Su-qin
dc.contributor.author	Lu, Guang-Hua
dc.contributor.author	Chan, Kelvin C.
dc.date.accessioned	2007-03-07T13:47:47Z
dc.date.available	2007-03-07T13:47:47Z
dc.date.issued	2006
dc.date.submitted	2007-02-01
dc.identifier.citation	Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 64(2): 321-326
dc.identifier.issn	1386-1425
dc.identifier.pmid	16386456
dc.identifier.doi	10.1016/j.saa.2005.07.026
dc.identifier.uri	http://hdl.handle.net/2436/9832
dc.description.abstract	In order to develop a rapid and effective analysis method for studying integrally the main constituents in the medicinal materials and their extracts, discriminating the extracts from different extraction process, comparing the categories of chemical constituents in the different extracts and monitoring the qualities of medicinal materials, we applied Fourier transform infrared spectroscopy (FT-IR) associated with second derivative infrared spectroscopy and two-dimensional correlation infrared spectroscopy (2D-IR) to study the main constituents in traditional Chinese medicine Angelica and its different extracts (extracted by petroleum ether, ethanol and water in turn). The findings indicated that FT-IR spectrum can provide many holistic variation rules of chemical constituents. Use of the macroscopical fingerprint characters of FT-IR and 2D-IR spectrum can not only identify the main chemical constituents in medicinal materials and their different extracts, but also compare the components differences among the similar samples. This analytical method is highly rapid, effective, visual and accurate for pharmaceutical research.
dc.format.extent	440400 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en
dc.publisher	Elsevier
dc.relation.url	http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VNG-4HX47S7-2&_user=1644469&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000054077&_version=1&_urlVersion=0&_userid=1644469&md5=96b2744837e2c0202a570ef1599391f7
dc.subject	Angelica
dc.subject	Fourier transform infrared spectroscopy
dc.subject	FT-IR
dc.subject	Chinese medicine
dc.title	Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy.
dc.type	Journal article
dc.format.dig	YES
refterms.dateFOA	2018-08-20T15:50:41Z
html.description.abstract	In order to develop a rapid and effective analysis method for studying integrally the main constituents in the medicinal materials and their extracts, discriminating the extracts from different extraction process, comparing the categories of chemical constituents in the different extracts and monitoring the qualities of medicinal materials, we applied Fourier transform infrared spectroscopy (FT-IR) associated with second derivative infrared spectroscopy and two-dimensional correlation infrared spectroscopy (2D-IR) to study the main constituents in traditional Chinese medicine Angelica and its different extracts (extracted by petroleum ether, ethanol and water in turn). The findings indicated that FT-IR spectrum can provide many holistic variation rules of chemical constituents. Use of the macroscopical fingerprint characters of FT-IR and 2D-IR spectrum can not only identify the main chemical constituents in medicinal materials and their different extracts, but also compare the components differences among the similar samples. This analytical method is highly rapid, effective, visual and accurate for pharmaceutical research.