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    Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy.

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    Authors
    Liu, Hong-xia
    Sun, Su-qin
    Lu, Guang-Hua
    Chan, Kelvin C.
    Issue Date
    2006
    Submitted date
    2007-02-01
    
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    Abstract
    In order to develop a rapid and effective analysis method for studying integrally the main constituents in the medicinal materials and their extracts, discriminating the extracts from different extraction process, comparing the categories of chemical constituents in the different extracts and monitoring the qualities of medicinal materials, we applied Fourier transform infrared spectroscopy (FT-IR) associated with second derivative infrared spectroscopy and two-dimensional correlation infrared spectroscopy (2D-IR) to study the main constituents in traditional Chinese medicine Angelica and its different extracts (extracted by petroleum ether, ethanol and water in turn). The findings indicated that FT-IR spectrum can provide many holistic variation rules of chemical constituents. Use of the macroscopical fingerprint characters of FT-IR and 2D-IR spectrum can not only identify the main chemical constituents in medicinal materials and their different extracts, but also compare the components differences among the similar samples. This analytical method is highly rapid, effective, visual and accurate for pharmaceutical research.
    Citation
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 64(2): 321-326
    Publisher
    Elsevier
    URI
    http://hdl.handle.net/2436/9832
    DOI
    10.1016/j.saa.2005.07.026
    PubMed ID
    16386456
    Additional Links
    http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VNG-4HX47S7-2&_user=1644469&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000054077&_version=1&_urlVersion=0&_userid=1644469&md5=96b2744837e2c0202a570ef1599391f7
    Type
    Journal article
    Language
    en
    ISSN
    1386-1425
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.saa.2005.07.026
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    Research Institute in Healthcare Science

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