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dc.contributor.authorGómez del Arco, Pablo
dc.contributor.authorMartínez-Martínez, Sara
dc.contributor.authorCalvo, Victor
dc.contributor.authorArmesilla, Angel Luis
dc.contributor.authorRedondo, Juan Miguel
dc.date.accessioned2007-01-24T14:45:23Z
dc.date.available2007-01-24T14:45:23Z
dc.date.issued1997
dc.date.submitted2007-01-24
dc.identifier.citationImmunobiology, 198(1-3): 273-278
dc.identifier.issn0171-2985
dc.identifier.pmid9442398
dc.identifier.urihttp://hdl.handle.net/2436/7746
dc.descriptionMetadata only
dc.description.abstractActivity of the transcription factor AP-1 is controlled by different MAPK cascades that regulate the different AP-1 components at the transcriptional and posttranscriptional level. Recently, AP-1 has been shown to behave as a redox-sensitive transcription factor that can be induced under both pro-oxidative and antioxidative conditions. In this overview we summarize the signaling pathways that converge on the activation of AP-1 and the components of these pathways that have been shown to be targets of antioxidants. The activation of AP-1 by antioxidants may account for the expression of a number of genes that mediate important functions under physiological conditions.
dc.language.isoen
dc.publisherElsevier BV
dc.relation.urlhttp://direct.bl.uk/bld/PlaceOrder.do?UIN=037406284&ETOC=RN&from=searchenginehttp://cat.inist.fr/?aModele=afficheN&cpsidt=10321900
dc.subjectTranscription factor
dc.subjectAP-1
dc.subjectAntioxidants
dc.titleAntioxidants and AP-1 activation: a brief overview.
dc.typeJournal article
dc.format.digYES
html.description.abstractActivity of the transcription factor AP-1 is controlled by different MAPK cascades that regulate the different AP-1 components at the transcriptional and posttranscriptional level. Recently, AP-1 has been shown to behave as a redox-sensitive transcription factor that can be induced under both pro-oxidative and antioxidative conditions. In this overview we summarize the signaling pathways that converge on the activation of AP-1 and the components of these pathways that have been shown to be targets of antioxidants. The activation of AP-1 by antioxidants may account for the expression of a number of genes that mediate important functions under physiological conditions.


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