Authors
Gómez del Arco, PabloMartínez-Martínez, Sara
Calvo, Victor
Armesilla, Angel
Redondo, Juan Miguel
Issue Date
1997Submitted date
2007-01-24
Metadata
Show full item recordAbstract
Activity of the transcription factor AP-1 is controlled by different MAPK cascades that regulate the different AP-1 components at the transcriptional and posttranscriptional level. Recently, AP-1 has been shown to behave as a redox-sensitive transcription factor that can be induced under both pro-oxidative and antioxidative conditions. In this overview we summarize the signaling pathways that converge on the activation of AP-1 and the components of these pathways that have been shown to be targets of antioxidants. The activation of AP-1 by antioxidants may account for the expression of a number of genes that mediate important functions under physiological conditions.Citation
Immunobiology, 198(1-3): 273-278Publisher
Elsevier BVPubMed ID
9442398Additional Links
http://direct.bl.uk/bld/PlaceOrder.do?UIN=037406284&ETOC=RN&from=searchenginehttp://cat.inist.fr/?aModele=afficheN&cpsidt=10321900Type
Journal articleLanguage
enDescription
Metadata onlyISSN
0171-2985Collections
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