3D printing customised stiffness-matched meta-biomaterial with near-zero auxeticity for load-bearing tissue repair
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AbstractThe evolution of meta-biomaterials has opened up exciting new opportunities for mass personalisation of biomedical devices. This research paper details the development of a CoCrMo meta-biomaterial structure that facilitates personalised stiffness-matching while also exhibiting near-zero auxeticity. Using laser powder bed fusion, the porous architecture of the meta-biomaterial was characterised, showing potential for near-zero Poisson’s ratio. The study also introduces a novel surrogate model that can predict the porosity (φ), yield strength (σy), elastic modulus (E), and negative Poisson’s ratio ( - υ) of the meta-biomaterial, which was achieved through prototype testing and numerical modelling. The model was then used to inform a multi-criteria desirability objective, revealing an optimum near-zero - υ of - 0.037, with a targeted stiffness of 17.21 GPa. Parametric analysis of the meta-biomaterial showed that it exhibited - υ, φ, σy and E values ranging from - 0.02 to -0.08, 73.63–81.38%, 41–64 MPa, and 9.46–20.6 GPa, respectively. In this study, a surrogate model was developed for the purpose of generating personalised scenarios for the production of bone scaffolds. By utilising this model, it was possible to achieve near-zero - υ and targeted stiffness personalisation. This breakthrough has significant implications for the field of bone tissue engineering and could pave the way for improved patient outcomes. The presented methodology is a powerful tool for the development of biomaterials and biomedical devices that can be 3D printed on demand for load-bearing tissue reconstruction. It has the potential to facilitate the creation of highly tailored and effective treatments for various conditions and injuries, ultimately enhancing patient outcomes.
CitationWanniarachchi, C.T., Arjunan, A., Baroutaji, A. and Singh, M. (2023) 3D printing customised stiffness-matched meta-biomaterial with near-zero auxeticity for load-bearing tissue repair. Bioprinting, 33, e00292.
Description© 2023 The Authors. Published by Elsevier. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1016/j.bprint.2023.e00292
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/