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dc.contributor.authorLowe, Chamodika
dc.contributor.authorKumarasinghe, Nishantha
dc.identifier.citationLowe C, Kumarasinghe N (2021) Identification of Social and Occupational Risk Factors Associated with CKDu (Chronic Kidney Disease of Unknown Etiology) Patients Living in an Agricultural Community in Kebithigollewa, Sri Lanka. International Journal of Nephrology and Kidney Failure 7(4):
dc.description© 2021 The Authors. Published by Sci Forschen Inc. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website:
dc.description.abstractAim: To identify the social and occupational risk factors associated with CKDu (Chronic Kidney Disease of unknown etiology) patients living in an agricultural community in Kebithigollewa, Sri Lanka. Methods: A three months community based cross sectional study was done involving 30 CKDu diagnosed patients who were attending the CKDu Western Ayurvedic Integrated Clinic at Kebithigollewa, North Central Province (NCP), Sri Lanka and 30 controls were taken from the same region. Socioeconomic and socio-demographic data was collected from the participants with the use of an interview administered questionnaire. Heights and weights were the anthropometric data measured for the study. Blood samples were collected as biochemical data which was later analysed using an automated blood analyser. Data collected was computerized and analysed using software Graphpad Prism 8 and SPSS version 20. Results: All the participants of the research were active residents living in the NCP since birth. 83.34% of the CKDu affected individuals were from the 4th to 7th decade of life and 70% of them were males. 86.66% of the affected population carried out agricultural practices as their main source of income with chena and paddy cultivation being the common practice followed. 96.66% of the affected were from low income families who earned 0-20000 LKR (Sri Lankan Rupee) per month. 40% of the affected have had only up to five years of school education. 63.33% of the CKDu patients were overweight. A significant correlation of 0.642218 was shown by Cramer’s V square test between Number of working hours/day and serum creatinine, indicating a strong association, but did not have a significant nominal logistic regression. Conclusion: Serum creatinine was high in farmers and laborers indicating that occupation impacts CKDu occurrence and progression. It was also high in the age group 31-50 yrs showing a significant relationship with serum creatinine which indicates the social impact on CKDu occurrence. A statistically significance of P <0.05 was shown by number of working hours and BMI (Body Mass Index).en
dc.publisherSci Forschen Inc.en
dc.subjectagricultural activitiesen
dc.subjectchronic kidney diseaseen
dc.subjectchronic kidney disease of unknown aetiologyen
dc.subjectheavy metalsen
dc.subjectnational research programme for CKDuen
dc.subjectSri Lankaen
dc.subjecttubulointerstitial nephritisen
dc.subjectWorld Health Organizationen
dc.titleIdentification of social and occupational risk factors associated with CKDu (chronic kidney disease of unknown etiology) patients living in an agricultural community in Kebithigollewa, Sri Lankaen
dc.typeJournal articleen
dc.identifier.journalInternational Journal of Nephrology and Kidney Failureen
rioxxterms.funderUniversity of Wolverhamptonen

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