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dc.contributor.authorSobejana, M
dc.contributor.authorvan den Hoek, J
dc.contributor.authorMetsios, GS
dc.contributor.authorKitas, GD
dc.contributor.authorJorstad, HT
dc.contributor.authorvan der Leeden, M
dc.contributor.authorPijnappels, M
dc.contributor.authorLems, WF
dc.contributor.authorNurmohamed, MT
dc.contributor.authorvan der Esch, M
dc.date.accessioned2021-08-19T14:13:37Z
dc.date.available2021-08-19T14:13:37Z
dc.date.issued2021-07-31
dc.identifier.citationSobejana, M., van den Hoek, J., Metsios, G.S. et al. (2021) Cardiorespiratory fitness and physical activity in people who have rheumatoid arthritis at an increased risk of cardiovascular disease: a cross-sectional study. Rheumatology International, 41, pp. 2177–2183. https://doi.org/10.1007/s00296-021-04903-6en
dc.identifier.issn0172-8172en
dc.identifier.pmid34331578 (pubmed)
dc.identifier.doi10.1007/s00296-021-04903-6en
dc.identifier.urihttp://hdl.handle.net/2436/624278
dc.descriptionThis is an accepted manuscript of an article published by Springer in Rheumatology International on 31/07/2021, available online: https://doi.org/10.1007/s00296-021-04903-6 The accepted version of the publication may differ from the final published version.en
dc.description.abstractLower cardiorespiratory fitness (CRF) and physical activity (PA) associate with higher cardiovascular disease (CVD) risk, but the relationship between CRF and PA in people who have rheumatoid arthritis (RA) at an increased CVD risk (CVD-RA) is not known. The objectives of this study were to determine the levels of CRF and PA in people who have CVD-RA and to investigate the association of CRF with PA in people who have CVD-RA. A total of 24 consecutive patients (19 women) with CVD-RA (> 4% for 10-year risk of fatal CVD development as calculated using the Systematic Coronary Risk Evaluation)-were included in the study. CRF was assessed with a graded maximal exercise test determining maximal oxygen uptake (VO<sub>2max</sub>). PA was assessed with an accelerometer to determine the amount of step count, sedentary, light and moderate-to-vigorous physical activity (MVPA) minutes per day. Mean age of patients was 65.3 ± 8.3 years. CRF mean values were 16.3 ± 1.2 ml·kg<sup>-1</sup> min<sup>-1</sup>, mean step count per day was 6033 ± 2256, and the mean MVPA time was 16.7 min per day. Significant positive associations were found for CRF with step count (B = 0.001, P = 0.01) and MVPA time (B = 0.15, P = 0.02); a negative association was found for CRF with sedentary time (B =  - 0.02, P = 0.03). CRF is low and is associated with step count, sedentary time and MVPA time in people who have RA at an increased CVD risk.en
dc.formatapplication/pdfen
dc.languageeng
dc.language.isoenen
dc.publisherSpringeren
dc.relation.urlhttps://link.springer.com/article/10.1007%2Fs00296-021-04903-6en
dc.subjectexerciseen
dc.subjectphysical activityen
dc.subjectcardiorespiratory fitnessen
dc.subjectcardiovascular diseaseen
dc.subjectrheumatoid arthritisen
dc.titleCardiorespiratory fitness and physical activity in people who have rheumatoid arthritis at an increased risk of cardiovascular disease: a cross-sectional studyen
dc.typeJournal articleen
dc.identifier.eissn1437-160X
dc.identifier.journalRheumatology Internationalen
dc.date.updated2021-08-19T12:23:43Z
dc.contributor.institutionReade, Center for Rehabilitation and Rheumatology, Amsterdam Rehabilitation Research Center | Reade, PO Box 58271, 1040 HG, Amsterdam, The Netherlands.
pubs.place-of-publicationGermany
dc.date.accepted2021-05-22
rioxxterms.funderUniversity of Wolverhamptonen
rioxxterms.identifier.projectUOW19082021GMen
rioxxterms.versionAMen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2022-07-31en
dc.source.volume41
dc.source.beginpage2177
dc.source.endpage2183
dc.description.versionPublished version
refterms.dateFCD2021-08-19T14:12:56Z
refterms.versionFCDAM


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