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dc.contributor.authorArjunan, Arun
dc.contributor.authorBaroutaji, Ahmad
dc.contributor.authorRobinson, John
dc.contributor.authorPraveen, Ayyappan S
dc.contributor.authorPollard, Andrew
dc.contributor.authorWang, Chang
dc.date.accessioned2021-03-01T15:29:53Z
dc.date.available2021-03-01T15:29:53Z
dc.date.issued2021-02-24
dc.identifier.citationArjunan, A., Baroutaji, A., Praveen, A.S. et al. (2021) Future directions and requirements for tissue engineering biomaterials. Reference Module in Materials Science and Materials Engineering. https://doi.org/10.1016/B978-0-12-815732-9.00068-1en
dc.identifier.isbn9780128035818en
dc.identifier.doi10.1016/b978-0-12-815732-9.00068-1en
dc.identifier.urihttp://hdl.handle.net/2436/623956
dc.descriptionThis is an accepted manuscript of an article published by Elsevier in Reference Module in Materials Science and Materials Engineering, available online: https://doi.org/10.1016/B978-0-12-815732-9.00068-1 The accepted version of the publication may differ from the final published version.en
dc.description.abstractA wide array of biomaterials are being developed to be used as tissue engineering scaffolds, including metals, ceramics, polymers, and composites. For all biomaterials, the challenge remains to achieve functionality to mimic the biomechanical environment, induce bioactivity, and support critical size tissue reintegration. This calls for a functional evolution in biomaterials to be used as tissue engineering constructs for partial and full tissue reconstruction. When characterizing biomaterials for tissue engineering, the relevant extensions include engineered surfaces, micro-patterns, and porous architectures along with, bioactive, bioresorbable, and infection resistant properties. Accordingly, functional biomaterials will drive the next generation of tissue engineering constructs. This paper, therefore, explores the major concepts, future direction, and recent signs of progress in the field of tissue engineering biomaterials. Traditional materials are not discounted entirely as bioinert materials are still relevant and emerging research offers new functionalities for them to support drug, gene, and cell tissue engineering. Therefore, an attempt is also made to explain how the requirements of biomaterials are changing to facilitate, sustain, control, and proliferate engineered tissue. The article begins with a brief introduction to the evolution of biomaterials followed by a commentary on their functional requirements when applied to tissue engineering. This is followed by an exploratory evaluation of key tissue engineering constructs and their qualifiers while systematically identifying their future direction and potential.en
dc.formatapplication/pdfen
dc.languageEnglish
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttps://www.sciencedirect.com/science/article/pii/B9780128157329000681en
dc.subjectAdditive manufacturingen
dc.subjectBiomaterialsen
dc.subjectBioprintingen
dc.subjectFunctional requirementsen
dc.subjectFuture direction; Regulationen
dc.subjectScaffoldsen
dc.subjecttissue engineeringen
dc.titleFuture directions and requirements for tissue engineering biomaterialsen
dc.typeBook chapteren
dc.identifier.journalReference Module in Materials Science and Materials Engineeringen
dc.date.updated2021-02-26T02:15:08Z
dc.date.accepted2021-02-01
rioxxterms.funderMHCLGen
rioxxterms.identifier.project01R19P03464en
rioxxterms.versionAMen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2023-02-24en
dc.description.versionPublished version
refterms.dateFCD2021-03-01T15:01:57Z
refterms.versionFCDAM


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