Mechanical performance of additively manufactured pure silver antibacterial bone scaffolds
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
AbstractImplant infection is a serious complication resulting in pain, mortality, prolonged recovery, and antimicrobial resistance (AMR). Reducing the risk-of-infection associated with tissue implants require imminent attention, where pure silver (Ag) offers enormous potential. However, the printability, mechanical performance nor microbial resistance of additively manufactured (AM) pure Ag is unavailable in literature. This is critical as Ag is thought to play a vital role in the development of AM patient-specific infection resistant implants in the decade to come. The study therefore additively manufactured 99.9% pure-Ag through selective laser melting (SLM) and systematically investigates its mechanical performance. The validated SLM process parameters were then used to conceive two fully porous bone scaffold each at approximately 68 and 90% (wt.) porosity. While the study brings to attention the potential defects in SLM pure-Ag through X-ray nanotomography (X-ray nCT), the mechanical properties of porous Ag scaffolds were found to be similar to cancellous bone. The study achieved the highest SLM pure-Ag density of 97% with Young’s modulus (E), elastic limit (), yield strength (), ultimate strength () and ultimate strain () in the range of 15.5–17.8 GPa, 50.7–57.7 MPa, 57.6–67.2 MPa, 82.4–95.9 MPa and 0.07–0.10 respectively. The antimicrobial efficacy of printed silver was tested against the common implant infection-causing Staphylococcus aureus and led to 90% and 99.9% kill in 4 and 14 h respectively. The study, therefore, is a first step towards achieving a new generation Ag-based AM infection resistant porous implants.
CitationArjunan, A., Robinson, J., Al Ani, E., Heaselgrave, W., Baroutaji, A. and Wang, C. (2020) Mechanical performance of additively manufactured pure silver antibacterial bone scaffolds, Journal of the Mechanical Behavior of Biomedical Materials, 112, 104090.
JournalJournal of the Mechanical Behavior of Biomedical Materials
DescriptionThis is an accepted manuscript of an article published by Elsevier in Journal of the Mechanical Behavior of Biomedical Materials on 22/09/2020, available online: https://doi.org/10.1016/j.jmbbm.2020.104090 The accepted version of the publication may differ from the final published version.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/