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dc.contributor.authorKumar, Rajiv
dc.contributor.authorGulia, Kiran
dc.contributor.authorChandra, Mina
dc.contributor.authorAggarwal, Anil K.
dc.contributor.authorKumar, Anil
dc.contributor.authorMittan, Sandeep
dc.contributor.authorMishra, Parashuram
dc.date.accessioned2020-09-11T13:36:32Z
dc.date.available2020-09-11T13:36:32Z
dc.date.issued2019-09-30
dc.identifier.issn2394-2274en
dc.identifier.urihttp://hdl.handle.net/2436/623626
dc.descriptionThis is an accepted manuscript of an article published by IS Publications in Journal of Biomedical & Therapeutic Sciences on 30/09/2020, available online: http://www.pubs.iscience.in/journal/index.php/jbts/article/view/926/594 The accepted version of the publication may differ from the final published version.en
dc.description.abstractAntibiotic drugs i.e. tetracycline and amoxicillin, were used mixed ligands (ML), for designing, architecturing, tailoring and synthesis for synthesis of supramolecular topologies of organometallic assemblies of Bi(V), represented as OMCs‐Bi(V), having O5 set for bonding. Molecular models were proposed as a standard to judge specific interactions in topologies of molecules of ML and derived organometallic assemblies. In OMCs‐Bi(V), on chelation, polarity of Bi(V) get reduced to great extent due to overlap of ML orbital. As a result, delocalization of π‐electrons density clouds get spread over the surface of chelating ring and enhances penetration power of OMCs‐Bi(V) into lipid membranes. This influenced binding with enzyme sites in microorganisms. Some electron set for bonding groups present in ligands moieties display extensive biological activity that may be responsible for increase in hydrophobic character and liposolubility of supramolecular topologies of organometallic of assemblies; ultimately enhanced biological activity of OMCs‐Bi(V).en
dc.formatapplication/pdfen
dc.languageEnglish
dc.language.isoenen
dc.publisherIntegrated Scienceen
dc.relation.urlhttp://pubs.iscience.in/journal/index.php/jbts/article/view/926en
dc.subjectOrganometallicen
dc.subjectnanoparticlesen
dc.subjectNanotechnologyen
dc.subjectAntibioticen
dc.titleBiomolecular interaction simulation of supramolecular topologies of organometallic assemblies of Bi(V) with antibiotic Tetracycline Amoxicillin drugs and their experimental activities evaluationen
dc.typeJournal articleen
dc.identifier.journalJournal of Biomedical and Therapeutic Sciencesen
dc.date.updated2020-08-26T13:09:03Z
dc.date.accepted2019-09-30
rioxxterms.funderUniversity of wolverhamptonen
rioxxterms.identifier.projectUOW11092020KGen
rioxxterms.versionAMen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2020-09-11en
refterms.dateFCD2020-09-11T13:25:40Z
refterms.versionFCDAM
refterms.dateFOA2020-09-11T13:36:34Z


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