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dc.contributor.authorHafstrom, Anna
dc.contributor.authorPatel, Mitesh
dc.contributor.authorModig, Fredrik
dc.contributor.authorMagnusson, Måns
dc.contributor.authorFransson, Per-Anders
dc.date.accessioned2020-08-04T09:33:50Z
dc.date.available2020-08-04T09:33:50Z
dc.date.issued2014-12-31
dc.identifier.citationHafstrom, A., Patel, M., Modig, F., Magnusson, M. and Fransson, P.A. (2014) Acute alcohol intoxication impairs segmental body alignment in upright standing, Journal of Vestibular Research, 24(4), pp. 297-304, DOI: 10.3233/VES-140513.en
dc.identifier.issn0957-4271en
dc.identifier.doi10.3233/ves-140513en
dc.identifier.urihttp://hdl.handle.net/2436/623425
dc.descriptionThis is an accepted manuscript of an article published by IOS Press in Journal of Vestibular Research 2014, available online: https://doi.org/10.3233/VES-140513 The accepted version of the publication may differ from the final published version.en
dc.description.abstractBalance control when standing upright is a complex process requiring input from several partly independent mechanisms such as coordination, feedback and feedforward control, and adaptation. Acute alcohol intoxication from ethanol is recognized as a major contributor to accidental falls requiring medical care. This study aimed to investigate if intoxication at 0.06 and 0.10% blood alcohol concentration affected body alignment. Mean angular positions of the head, shoulder, hip, and knee were measured with 3D-motion analysis and compared with the ankle position in 25 healthy adults during standing with or without perturbations, and with eyes open or closed. Alcohol intoxication had significant effects on body alignment during perturbed and unperturbed stance, and on adaptation to perturbations. It induced a significantly more posterior alignment of the knees and shoulders, and a tendency for a more posterior and left deviated head alignment in perturbed stance than when sober. The impact of alcohol intoxication was most apparent on the knee alignment, where availability of visual information deteriorated the adaptation to perturbations. Thus, acute alcohol intoxication resulted in inadequate balance control strategies with increased postural rigidity and impaired adaptation to perturbations. These factors probably contribute to the increased risk of falling when intoxicated with alcohol.en
dc.formatapplication/pdfen
dc.language.isoenen
dc.publisherIOS Pressen
dc.relation.urlhttps://content.iospress.com/articles/journal-of-vestibular-research/ves00513en
dc.subjectethanolen
dc.subjectbalanceen
dc.subjectpostural controlen
dc.subjectvisionen
dc.subjectadaptationen
dc.titleAcute alcohol intoxication impairs segmental body alignment in upright standingen
dc.typeJournal articleen
dc.identifier.journalJournal of Vestibular Researchen
dc.date.updated2020-07-24T09:46:25Z
dc.date.accepted2014-03-12
rioxxterms.funderImperial College Londonen
rioxxterms.identifier.projectUOW04082020MPen
rioxxterms.versionAMen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2020-08-04en
dc.source.volume24
dc.source.issue4
dc.source.beginpage297
dc.source.endpage304
dc.description.versionPublished version
refterms.dateFCD2020-08-04T09:31:40Z
refterms.versionFCDAM
refterms.dateFOA2020-08-04T00:00:00Z


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