AbstractConclusion: Elevated Motion Sickness Susceptibility (MSS) in Meniere?s disease (MD) is likely to be a consequence of the onset of MD and not migraine per se. Objectives: Pathologies of the vestibular system influence MSS. Bilateral vestibular deficits lower MSS, vestibular neuritis or benign paroxysmal positional vertigo have little overall effect, whereas vestibular migraine elevates MSS. However, less is known about MSS in MD, a condition in which many patients experience vestibular loss and migraine symptoms. Methods: The authors conducted an online survey that posed diagnostic and disease questions before addressing frequency of headaches, migraines, visual display dizziness (VDD), syncope, social life, and work impact of dizziness (SWID4) and motion sickness susceptibility (MSSQ). The two groups were: diagnosed MD individuals with hearing loss (n = 751) and non-MD individuals in the control group (n = 400). Results: The MD group showed significantly elevated MSS, more headache and migraine, increased VDD, higher SWID4 scores, and increased syncope. MSS was higher in MD than controls only after the development of MD, but not before, nor in childhood. Although elevated in MD compared with controls, MSS was lower than migraine patients from past data. Multivariate analysis revealed VDD, SWID4, and MSS in adulthood as the strongest predictors of MD, but not headache nor migraine.
CitationGolding, J. F. and Patel, M. (2017) Meniere’s, migraine, and motion sickness, Acta Oto-Laryngologica, 137(5) pp. 495-502. DOI: 10.1080/00016489.2016.1255775
PublisherInforma UK Limited
DescriptionThis is an accepted manuscript of an article published by Taylor and Francis in Oto-Laryngologica on 05/12/2016, available online: https://doi.org/10.1080/00016489.2016.1255775 The accepted version of the publication may differ from the final published version.
SponsorsThe research was supported by the National Institute for Health Research (NIHR) Imperial Biomedical Research Centre.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/