Show simple item record

dc.contributor.authorPasaribu, Khatarina Meldawati
dc.contributor.authorGea, Saharman
dc.contributor.authorIlyas, Syafruddin
dc.contributor.authorTamrin, Tamrin
dc.contributor.authorSarumaha, Appealwan Altruistis
dc.contributor.authorSembiring, Ardiansyah
dc.contributor.authorRadecka, Izabela
dc.date.accessioned2020-07-21T13:14:07Z
dc.date.available2020-07-21T13:14:07Z
dc.date.issued2020-06-27
dc.identifier.citationPasaribu, K.M.; Gea, S.; Ilyas, S.; Tamrin, T.; Sarumaha, A.A.; Sembiring, A.; Radecka, I. (2020) Fabrication and In-Vivo Study of Micro-Colloidal Zanthoxylum acanthopodium-Loaded Bacterial Cellulose as a Burn Wound Dressing. Polymers, 12(7), 1436.en
dc.identifier.issn2073-4360en
dc.identifier.doi10.3390/polym12071436en
dc.identifier.urihttp://hdl.handle.net/2436/623376
dc.description© 2020 The Authors. Published by MDPI. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.3390/polym12071436en
dc.description.abstractBacterial cellulose (BC) is a biopolymer commonly used for wound dressing due to its high biocompatible properties either in-vitro or in-vivo. The three-dimensional fiber structure of BC becomes an advantage because it provides a template for the impregnation of materials in order to improve BC’s properties as a wound dressing, since BC has not displayed any bioactivity properties. In this study, micro-colloidal Zanthoxylum acanthopodium (MZA) fruit was loaded into BC fibers via an in-situ method. Z. acanthopodium is known to have anti-inflammatory, antioxidant and antimicrobial activities that can support BC to accelerate the wound healing process. The FTIR, XRD and SEM analysis results showed that the loading process of MZA and the composite fabrication were successfully carried out. The TGA test also showed that the presence of MZA in BC fibers decreased Tmax composite from BC, from 357.8 to 334.5 °C for BC-MZA3. Other aspects, i.e., water content, porosity, hemocompatibility and histology studies, also showed that the composite could potentially be used as a wound dressing.en
dc.description.sponsorshipThis research was fully funded by the Ministry of Research, Technology and Higher Education through 2018 PMDSU Research Scheme (Grant no: 1/UN5.2.3.1/PPM/KP-DRPM-PMDSU II/2018).en
dc.formatapplication/pdfen
dc.languageen
dc.language.isoenen
dc.publisherMDPIen
dc.relation.urlhttps://www.mdpi.com/2073-4360/12/7/1436en
dc.subjectbacterial celluloseen
dc.subjectMZAen
dc.subjectBC-MZAen
dc.subjectcompositeen
dc.subjectwound dressingen
dc.titleFabrication and in-vivo study of micro-colloidal zanthoxylum acanthopodium-loaded bacterial cellulose as a burn wound dressingen
dc.typeJournal articleen
dc.identifier.journalPolymersen
dc.date.updated2020-07-01T08:40:46Z
dc.date.accepted2020-06-25
rioxxterms.funderMinistry of Research, Technology and Higher Educationen
rioxxterms.identifier.project1/UN5.2.3.1/PPM/KP-DRPM-PMDSU II/2018en
rioxxterms.versionVoRen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2020-07-21en
dc.source.volume12
dc.source.issue7
dc.source.beginpage1436
dc.source.endpage1436
dc.description.versionPublished online
refterms.dateFCD2020-07-21T13:13:53Z
refterms.versionFCDVoR
refterms.dateFOA2020-07-21T13:14:10Z


Files in this item

Thumbnail
Name:
Fabrication and In-Vivo Study ...
Size:
7.686Mb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record

https://creativecommons.org/licenses/by/4.0/
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/