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dc.contributor.authorIdrees, Muhammad
dc.contributor.authorMohammad, Afzal R
dc.contributor.authorKarodia, Nazira
dc.contributor.authorRahman, Ayesha
dc.date.accessioned2020-07-03T15:00:19Z
dc.date.available2020-07-03T15:00:19Z
dc.date.issued2020-06-17
dc.identifier.citationIdrees, M., Mohammad, A.R., Karodia, N. and Rahman, A. (2020) Multimodal Role of Amino Acids in Microbial Control and Drug Development. Antibiotics 2020, 9, 330.en
dc.identifier.issn2079-6382en
dc.identifier.doi10.3390/antibiotics9060330en
dc.identifier.urihttp://hdl.handle.net/2436/623324
dc.description© 2020 The Authors. Published by MDPI. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.3390/antibiotics9060330en
dc.description.abstractAmino acids are ubiquitous vital biomolecules found in all kinds of living organisms including those in the microbial world. They are utilised as nutrients and control many biological functions in microorganisms such as cell division, cell wall formation, cell growth and metabolism, intermicrobial communication (quorum sensing), and microbial-host interactions. Amino acids in the form of enzymes also play a key role in enabling microbes to resist antimicrobial drugs. Antimicrobial resistance (AMR) and microbial biofilms are posing a great threat to the world’s human and animal population and are of prime concern to scientists and medical professionals. Although amino acids play an important role in the development of microbial resistance, they also offer a solution to the very same problem i.e., amino acids have been used to develop antimicrobial peptides as they are highly effective and less prone to microbial resistance. Other important applications of amino acids include their role as anti-biofilm agents, drug excipients, drug solubility enhancers, and drug adjuvants. This review aims to explore the emerging paradigm of amino acids as potential therapeutic moieties.en
dc.formatapplication/pdfen
dc.languageen
dc.language.isoenen
dc.publisherMDPI AGen
dc.relation.urlhttps://www.mdpi.com/2079-6382/9/6/330en
dc.subjectamino acidsen
dc.subjectantimicrobial resistanceen
dc.subjectquorum sensingen
dc.subjectmicrobial biofilmen
dc.subjectsolubilityen
dc.subjectexcipientsen
dc.subjectadjuvantsen
dc.titleMultimodal role of amino acids in microbial control and drug developmenten
dc.typeJournal articleen
dc.identifier.eissn2079-6382
dc.identifier.journalAntibioticsen
dc.date.updated2020-06-25T19:06:31Z
dc.date.accepted2020-06-16
rioxxterms.funderUniversity of Wolverhamptonen
rioxxterms.identifier.projectUOW03072020ARen
rioxxterms.versionVoRen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2020-07-03en
dc.source.volume9
dc.source.issue6
dc.source.beginpage330
dc.source.endpage330
dc.description.versionPublished online
refterms.dateFCD2020-07-03T14:58:12Z
refterms.versionFCDVoR
refterms.dateFOA2020-07-03T15:00:19Z


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