Enhanced erythrocyte antioxidant status following an 8-week aerobic exercise training program in heavy drinkers
Authors
Jamurtas, Athanasios ZGeorgakouli, Kalliopi
Manthou, Eirini
Georgoulias, Panagiotis
Deli, Chariklia
Koutedakis, Yiannis

Theodorakis, Yannis
Fatouros, Ioannis
Issue Date
2018-05-31
Metadata
Show full item recordAbstract
Alcohol-induced oxidative stress is involved in the development and progression of various pathological conditions and diseases whereas exercise training has been shown to improve redox status, thus attenuating oxidative stress-associated disease processes. PURPOSE: to evaluate the effect of an exercise training program on blood redox status in heavy drinkers. METHODS: Eleven sedentary, heavy drinking men participated in an intervention where they completed an 8-week supervised aerobic training program of moderate intensity. Blood samples were collected before, during (week 4) and after intervention and analyzed for total antioxidant capacity (TAC), thiobarbituric acid reactive substances (TBARS), protein carbonyls (PC), uric acid (UA), bilirubin, reduced glutathione (GSH) and catalase activity. RESULTS: Catalase activity increased (p<0.05) after 8 weeks (340.7+13.3 U mg/Hb) of intervention compared to week 4 (299.5+18.7 U mg/Hb). GSH increased (p<0.05) after 8 weeks of intervention (1.22+0.16 μmol/g Hb) compared to the control condition (1.11 + 0.17 μmol/g Hb) and to week 4 (1.11 + 0.15 μmol/g Hb ). TAC, UA, bilirubin, TBARS and PC did not significantly change at any time point. CONCLUSION: An 8-week aerobic training program enhanced erythrocyte antioxidant status in heavy drinkers, indicating that aerobic training may attenuate pathological processes caused by alcohol-induced oxidative stress.Citation
Jamurtas, A.Z., Georgakouli, K., Manthou, E. et al. (2018) Enhanced erythrocyte antioxidant status following an 8-week aerobic exercise training program in heavy drinkers, Medicine and Science in Sports and Exercise, 50(5S), pp. 837-838.Publisher
American College of Sports MedicineJournal
Medicine and Science in Sports and ExerciseAdditional Links
https://journals.lww.com/acsm-msse/Fulltext/2018/05001/Enhanced_Erythrocyte_Antioxidant_Status_Following.2766.aspxType
OtherLanguage
enISSN
0195-9131EISSN
1530-0315ae974a485f413a2113503eed53cd6c53
10.1249/01.mss.0000538757.35067.ca
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