Association between anemia and blood transfusion with long-term mortality after cardiac surgery
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
AbstractBACKGROUND:Preoperative anemia and red blood cell (RBC) transfusion are both associated with in-hospital mortality after cardiac surgery. The aim of this study was to investigate the interactions between preoperative anemia and RBC transfusion and their effect on the long-term survival of patients undergoing cardiac surgery. METHODS:Between 2005 and 2012, 1170 patients with anemia who underwent elective or urgent cardiac surgery were included. A matched group of 1170 nonanemic patients was used as a control group. A binary logistic regression model was used. RESULTS:The median follow-up period was 64 months (range, 0-127). Anemic patients had higher mortality (45%, n = 526) than nonanemic patients (32%, n = 374; P < .001). Preoperative anemia was independently associated with long-term mortality (odds ratio [OR], 1.70; 95% confidence interval [CI], 1.46-2.1; P < .001), with both moderate (OR, 2.27; 95% CI, 1.72-2.99; P < .001) and mild anemia (OR, 1.39; 95% CI, 1.13-1.71; P = .002) contributing significantly. RBC transfusion was not associated with long-term mortality (OR, 1.07; 95% CI, 0.88-1.31; P = .49). There was no interaction between preoperative anemia and RBC transfusion (P = .947). CONCLUSIONS:Long-term mortality is significantly high in patients who are anemic, regardless of their transfusion status. Preoperative anemia is a strong, independent predictor of mortality and therefore should be managed before cardiac surgery.
CitationPadmanabhan, H., Brookes, M. J., Nevill, A. M. and Luckraz, H. (2019) Association between anemia and blood transfusion with long-term mortality after cardiac surgery, The Annals of Thoracic Surgery, 108(3), pp. 687-692.
JournalThe Annals of Thoracic Surgery
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/
- Relationship Between Preoperative Anemia and In-Hospital Mortality in Children Undergoing Noncardiac Surgery.
- Authors: Faraoni D, DiNardo JA, Goobie SM
- Issue date: 2016 Dec
- Treating Anemia in the Preanesthesia Assessment Clinic: Results of a Retrospective Evaluation.
- Authors: Ellermann I, Bueckmann A, Eveslage M, Buddendick H, Latal T, Niehoff D, Geissler RG, Hempel G, Kerkhoff A, Berdel WE, Roeder N, Van Aken HK, Zarbock A, Steinbicker AU
- Issue date: 2018 Nov
- Preoperative anemia versus blood transfusion: Which is the culprit for worse outcomes in cardiac surgery?
- Authors: LaPar DJ, Hawkins RB, McMurry TL, Isbell JM, Rich JB, Speir AM, Quader MA, Kron IL, Kern JA, Ailawadi G, Investigators for the Virginia Cardiac Services Quality Initiative.
- Issue date: 2018 Jul
- Anemia in cardiac surgery: next target for mortality and morbidity improvement?
- Authors: Padmanabhan H, Aktuerk D, Brookes MJ, Nevill AM, Ng A, Cotton J, Luckraz H
- Issue date: 2016 Jan
- The least of 3 evils: exposure to red blood cell transfusion, anemia, or both?
- Authors: Loor G, Rajeswaran J, Li L, Sabik JF 3rd, Blackstone EH, McCrae KR, Koch CG
- Issue date: 2013 Dec