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dc.contributor.authorWright, Bernice
dc.contributor.authorEmmanuel, Anton
dc.contributor.authorAthanasakos, Eleni
dc.contributor.authorParmar, Nina
dc.contributor.authorParker, Georgina
dc.contributor.authorGreen, Belinda
dc.contributor.authorTailby, Emma
dc.contributor.authorChandler, Heidi
dc.contributor.authorCushnie, Julyette
dc.contributor.authorPembroke, June
dc.contributor.authorSaruchera, Yvonne
dc.contributor.authorVashisht, Arvind
dc.contributor.authorDay, Richard
dc.date.accessioned2019-08-14T12:11:17Z
dc.date.available2019-08-14T12:11:17Z
dc.date.issued2016-02
dc.identifier.citationWright, B., Emmanuel, A., Athanasakos, E., Parmar, N., Parker, G., Green, B., Tailby, E., Chandler, H., Cushnie, J., Pembroke, J., Saruchera, Y., Vashisht, A. and & Day, R. (2016) Women's views on autologous cell-based therapy for post-obstetric incontinence, Regenerative Medicine, 11(2), pp. 169-180.en
dc.identifier.issn1746-0751en
dc.identifier.doi10.2217/rme.15.88en
dc.identifier.urihttp://hdl.handle.net/2436/622647
dc.description.abstractAim: Fecal and urinary incontinence are devastating consequences of obstetric-related perineal injury. The aim of the present study is to determine acceptability to parous women of autologous cell-based therapy for fecal and urinary incontinence that arises due to pelvic diaphragm tearing during vaginal childbirth. Materials & methods: A multiple choice questionnaire survey was offered to 76 parous women at the Maternity Unit, University College Hospital, London, UK. Seventy completed questionnaires – response rate: 92%. Results: In total, 84% of women indicated a willingness to accept autologous cell-based therapy for obstetric injury-induced incontinence rather than surgery. Conclusion: These observational data provide an indication of likely acceptance of autologous cell-based therapies for birth injury incontinence and will help with designing new therapeutic approaches.en
dc.description.sponsorshipThe project was supported by grants from the UK Medical Research Council (MR/L002752/1), The Sir Halley Stewart Trust, The Henry Smith Charity, and the UCL Grand Challenge Studentship Scheme. The research was undertaken at UCL/UCLH which receives funding from the Department of Health's NIHR as a Comprehensive Biomedical Research Centre.en
dc.formatapplication/PDFen
dc.languageen
dc.language.isoenen
dc.publisherFuture Medicineen
dc.relation.urlhttps://www.futuremedicine.com/doi/10.2217/rme.15.88en
dc.subjectanal sphincteren
dc.subjectautologous stem cell therapyen
dc.subjectfecal incontinenceen
dc.subjectobstetric injuryen
dc.subjectpatient preferenceen
dc.subjecturinary incontinenceen
dc.titleWomen's views on autologous cell-based therapy for post-obstetric incontinenceen
dc.typeJournal articleen
dc.identifier.eissn1746-076X
dc.identifier.journalRegenerative Medicineen
dc.date.updated2019-08-12T13:22:40Z
dc.date.accepted2016-02
rioxxterms.funderUniversity of Wolverhamptonen
rioxxterms.identifier.projectMR/L002752/1en
rioxxterms.versionAMen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2019-08-14en
dc.source.volume11
dc.source.issue2
dc.source.beginpage169
dc.source.endpage180
dc.description.versionPublished version
refterms.dateFCD2019-08-14T12:09:30Z
refterms.versionFCDAM
refterms.dateFOA2019-08-14T12:11:17Z


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