The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.
Authors
Pangeni, Rajendra PChannathodiyil, Prasanna
Huen, David S
Eagles, Lawrence W
Johal, Balraj K
Pasha, Dawar
Hadjistephanou, Natasa
Nevell, Oliver
Davies, Claire L
Adewumi, Ayobami I
Khanom, Hamida
Samra, Ikroop S
Buzatto, Vanessa C
Chandrasekaran, Preethi
Shinawi, Thoraia
Dawson, Timothy P
Ashton, Katherine
Davis, Charles
Brodbelt, Andrew R
Jenkinson, Michael D
Bièche, Ivan
Latif, Farida
Darling, John L
Warr, Tracy J
Morris, Mark R.
Issue Date
2015-05-27
Metadata
Show full item recordAbstract
Tumour metastasis to the brain is a common and deadly development in certain cancers; 18-30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood.Citation
Pangeni, R.P., Channathodiyil, P., Huen, D.S. et al. The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain. Clin Epigenet 7, 57 (2015). https://doi.org/10.1186/s13148-015-0089-xPublisher
BioMed CentralJournal
Clinical epigeneticsPubMed ID
26052355Type
Journal articleLanguage
enISSN
1868-7075ae974a485f413a2113503eed53cd6c53
10.1186/s13148-015-0089-x
Scopus Count
Collections
Related articles
- Genome-wide methylation analyses identifies Non-coding RNA genes dysregulated in breast tumours that metastasise to the brain.
- Authors: Pangeni RP, Olivaries I, Huen D, Buzatto VC, Dawson TP, Ashton KM, Davis C, Brodbelt AR, Jenkinson MD, Bièche I, Yang L, Latif F, Darling JL, Warr TJ, Morris MR
- Issue date: 2022 Jan 20
- Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma.
- Authors: Morris MR, Ricketts CJ, Gentle D, McRonald F, Carli N, Khalili H, Brown M, Kishida T, Yao M, Banks RE, Clarke N, Latif F, Maher ER
- Issue date: 2011 Mar 24
- Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancer.
- Authors: Birgisdottir V, Stefansson OA, Bodvarsdottir SK, Hilmarsdottir H, Jonasson JG, Eyfjord JE
- Issue date: 2006
- Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours.
- Authors: Honorio S, Agathanggelou A, Wernert N, Rothe M, Maher ER, Latif F
- Issue date: 2003 Jan 23
- Semaphorin-plexin signalling genes associated with human breast tumourigenesis.
- Authors: Gabrovska PN, Smith RA, Tiang T, Weinstein SR, Haupt LM, Griffiths LR
- Issue date: 2011 Dec 10