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    The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.

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    Authors
    Pangeni, Rajendra P
    Channathodiyil, Prasanna
    Huen, David S
    Eagles, Lawrence W
    Johal, Balraj K
    Pasha, Dawar
    Hadjistephanou, Natasa
    Nevell, Oliver
    Davies, Claire L
    Adewumi, Ayobami I
    Khanom, Hamida
    Samra, Ikroop S
    Buzatto, Vanessa C
    Chandrasekaran, Preethi
    Shinawi, Thoraia
    Dawson, Timothy P
    Ashton, Katherine
    Davis, Charles
    Brodbelt, Andrew R
    Jenkinson, Michael D
    Bièche, Ivan
    Latif, Farida
    Darling, John L
    Warr, Tracy J
    Morris, Mark R.
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    Issue Date
    2015-05-27
    
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    Abstract
    Tumour metastasis to the brain is a common and deadly development in certain cancers; 18-30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood.
    Citation
    Pangeni, R.P., Channathodiyil, P., Huen, D.S. et al. The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain. Clin Epigenet 7, 57 (2015). https://doi.org/10.1186/s13148-015-0089-x
    Publisher
    BioMed Central
    Journal
    Clinical epigenetics
    URI
    http://hdl.handle.net/2436/621319
    DOI
    10.1186/s13148-015-0089-x
    PubMed ID
    26052355
    Type
    Journal article
    Language
    en
    ISSN
    1868-7075
    ae974a485f413a2113503eed53cd6c53
    10.1186/s13148-015-0089-x
    Scopus Count
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