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dc.contributor.authorYates, Sally A
dc.contributor.authorDempster, Nicola M
dc.contributor.authorMurphy, Mark F
dc.contributor.authorMoore, Sharon A
dc.date.accessioned2017-12-20T16:54:08Z
dc.date.available2017-12-20T16:54:08Z
dc.date.issued2017-04-16
dc.identifier.citationYates, SA., Dempster, NM., Murphy, MF and Moore, SA. (2017) 'Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry'. Rapid Communications In Mass Spectrometry. 31 (9) pp. 762-770
dc.identifier.pmid28231608
dc.identifier.doi10.1002/rcm.7843
dc.identifier.urihttp://hdl.handle.net/2436/621014
dc.description.abstractThe lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.
dc.language.isoen
dc.publisherWiley
dc.titleQuantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry
dc.typeJournal article
dc.identifier.journalRapid Communications In Mass Spectrometry
dc.date.accepted2017-02-21
rioxxterms.funderUniversity of Wolverhampton ERAS Fund
rioxxterms.identifier.projectUOW201217
rioxxterms.versionAM
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
rioxxterms.licenseref.startdate2018-05-16
dc.source.volume31
dc.source.issue9
dc.source.beginpage762
dc.source.endpage770
refterms.dateFCD2018-10-19T09:26:31Z
refterms.versionFCDAM
refterms.dateFOA2018-05-16T00:00:00Z
html.description.abstractThe lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.


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