Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry
Abstract
The lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.Citation
Yates, SA., Dempster, NM., Murphy, MF and Moore, SA. (2017) 'Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry'. Rapid Communications In Mass Spectrometry. 31 (9) pp. 762-770Publisher
WileyJournal
Rapid Communications In Mass SpectrometryDOI
10.1002/rcm.7843PubMed ID
28231608Type
Journal articleLanguage
enae974a485f413a2113503eed53cd6c53
10.1002/rcm.7843
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- Creative Commons
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/
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