Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry

Yates, Sally A; Dempster, Nicola M; Murphy, Mark F; Moore, Sharon A

Name:

S Moore RCMS 2017.pdf

Size:

972.8Kb

Format:

PDF

Download

Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item. When enough users have cast their vote on this item, the average rating will also be shown.

Star rating

Your vote was cast
Thank you for your feedback

Authors

Yates, Sally A
Dempster, Nicola M
Murphy, Mark F
Moore, Sharon A

Issue Date

2017-05-16

Metadata

Show full item record

Abstract

The lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.

Citation

Yates, SA., Dempster, NM., Murphy, MF and Moore, SA. (2017) 'Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry'. Rapid Communications In Mass Spectrometry. 31 (9) pp. 762-770

Publisher

Wiley

Journal

Rapid Communications In Mass Spectrometry

URI

http://hdl.handle.net/2436/621014

DOI

10.1002/rcm.7843

PubMed ID

28231608

Type

Journal article

Language

Collections

Faculty of Science and Engineering

The following license files are associated with this item:

Creative Commons