LDL particle size in habitual exercisers, lean sedentary men and abdominally obese sedentary men.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
AbstractHabitual exercisers enjoy considerable protection from coronary heart disease (CHD). Often, however, only modest differences in traditional CHD risk factors are apparent between habitual exercisers and their sedentary counterparts. For this reason, there is increasing interest in novel predictors of CHD, such as a preponderance of small, dense low-density lipoprotein (LDL) particles. Polyacrylamide gel electrophoresis was used to separate lipoprotein subfractions in 32 lean exercisers, 36 lean sedentary men and 21 obese sedentary men aged 30 - 45 years. Well-validated equations were used to determine LDL concentration and peak particle diameter. Waist girth was used to identify lean (< 100 cm) and obese (>or= 100 cm) individuals. LDL concentration was lower in lean exercisers than in lean sedentary men (2.64 +/- 0.44 vs. 3.76 +/- 0.79 mmol . l (-1), p < 0.001), suggesting that habitual exercise influences this risk factor. In contrast, there were no significant differences in LDL peak particle diameter between lean exercisers, lean sedentary men and obese sedentary men (27.92 +/- 0.67, 28.09 +/- 0.62 and 27.77 +/- 0.77 nm, respectively). In multiple linear regression analysis, triglyceride concentration was the only significant predictor of LDL PPD. These data suggest that habitual exercise influences LDL concentration but does not influence LDL particle size in men aged 30 - 45 years.
CitationLDL particle size in habitual exercisers, lean sedentary men and abdominally obese sedentary men. 2007, 28 (8):644-9 Int J Sports Med
JournalInternational journal of sports medicine
- Cardiovascular disease risk factors in habitual exercisers, lean sedentary men and abdominally obese sedentary men.
- Authors: O'Donovan G, Owen A, Kearney EM, Jones DW, Nevill AM, Woolf-May K, Bird SR
- Issue date: 2005 Sep
- Low-density lipoprotein (LDL) particle size in healthy prepubertal children: the STRIP study.
- Authors: Kaitosaari T, Rönnemaa T, Viikari J, Leino A, Jokinen E, Simell O
- Issue date: 2006 Dec
- Effect of plant sterols and endurance training on LDL particle size and distribution in previously sedentary hypercholesterolemic adults.
- Authors: Varady KA, St-Pierre AC, Lamarche B, Jones PJ
- Issue date: 2005 Apr
- Alterations of atherogenic low-density lipoproteins and serum fatty acids after 12 week moderate exercise training in sedentary Thai women.
- Authors: Sittiwicheanwong R, Ariyapitipun T, Gulsatitporn S, Nopponpunth V, Abeywardena M, Dahlan W
- Issue date: 2007
- Baseline triglyceride levels and insulin sensitivity are major determinants of the increase of LDL particle size and buoyancy induced by rosuvastatin treatment in patients with primary hyperlipidemia.
- Authors: Kostapanos MS, Milionis HJ, Lagos KG, Rizos CB, Tselepis AD, Elisaf MS
- Issue date: 2008 Aug 20