Essential oils and metal ions as alternative antimicrobial agents: a focus on tea tree oil and silver.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
AbstractThe increasing occurrence of hospital-acquired infections and the emerging problems posed by antibiotic-resistant microbial strains have both contributed to the escalating cost of treatment. The presence of infection at the wound site can potentially stall the healing process at the inflammatory stage, leading to the development of a chronic wound. Traditional wound treatment regimes can no longer cope with the complications posed by antibiotic-resistant strains; hence, there is a need to explore the use of alternative antimicrobial agents. Pre-antibiotic compounds, including heavy metal ions and essential oils, have been re-investigated for their potential use as effective antimicrobial agents. Essential oils have potent antimicrobial, antifungal, antiviral, anti-inflammatory, antioxidant and other beneficial therapeutic properties. Similarly, heavy metal ions have also been used as disinfecting agents because of their broad spectrum activities. Both of these alternative antimicrobials interact with many different intracellular components, thereby resulting in the disruption of vital cell functions and eventually cell death. This review will discuss the application of essential oils and heavy metal ions, particularly tea tree oil and silver ions, as alternative antimicrobial agents for the treatment of chronic, infected wounds.
CitationLow, W., Kenward, K., Britland, ST., Amin, MC., Martin, C. (2016) 'Essential oils and metal ions as alternative antimicrobial agents: a focus on tea tree oil and silver', International Wound Journal, 14(2) pp. 369-384. doi: 10.1111/iwj.12611
JournalInternational Wound Journal
The following licence applies to the copyright and re-use of this item:
- Creative Commons
- Staphylococcus aureus and wounds: a review of tea tree oil as a promising antimicrobial.
- Authors: Halcón L, Milkus K
- Issue date: 2004 Nov
- Uncontrolled, open-label, pilot study of tea tree (Melaleuca alternifolia) oil solution in the decolonisation of methicillin-resistant Staphylococcus aureus positive wounds and its influence on wound healing.
- Authors: Edmondson M, Newall N, Carville K, Smith J, Riley TV, Carson CF
- Issue date: 2011 Aug
- The influence of essential oils on the process of wound healing: a review of the current evidence.
- Authors: Woollard AC, Tatham KC, Barker S
- Issue date: 2007 Jun
- Appropriate use of dressings containing nanocrystalline silver to support antimicrobial stewardship in wounds.
- Authors: Woodmansey EJ, Roberts CD
- Issue date: 2018 Dec
- Percutaneous treatment of chronic MRSA osteomyelitis with a novel plant-derived antiseptic.
- Authors: Sherry E, Boeck H, Warnke PH
- Issue date: 2001