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    Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates

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    Authors
    Kaialy, Waseem
    Gorman, Terry
    Hussain, Tariq
    Armour-Chélu, David
    Deng, Tong
    Bradley, Michael Samuel Arthur
    Issue Date
    2016-08-01
    
    Metadata
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    Abstract
    Electrostatic charge due to inter-particle and particle-wall contacts may generate significant hazards during the processing of particulates within the pharmaceutical industry. Although charge behaviour of particulates is erratic and not easy to predict, it would be desirable to characterise the tendency of tribocharging prior to manufacturing. The work reported in this paper concentrates on a new and novel techniques for the detection of the active ingredient and excipient in a bipolar material. Three different case studies are presented for demonstration of the applicability of the method in different practical situations. Work confirmed through an experimental rig set-up indicates that materials that accumulate opposite charge via contact and rubbing can be detected from their charge sign as well as their relative magnitude. The results reported clearly demonstrated that the developed method for charge characterisation is a useful tool to understand how the charges are distributed in a population of particles showing a number of advantages over conventional methods.
    Citation
    Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates 2016 IET Science, Measurement & Technology
    Publisher
    IET Digital Library
    Journal
    IET Science, Measurement & Technology
    URI
    http://hdl.handle.net/2436/605453
    DOI
    10.1049/iet-smt.2015.0194
    Additional Links
    http://digital-library.theiet.org/content/journals/10.1049/iet-smt.2015.0194
    Type
    Journal article
    Language
    en
    ISSN
    1751-8822
    1751-8830
    ae974a485f413a2113503eed53cd6c53
    10.1049/iet-smt.2015.0194
    Scopus Count
    Collections
    Faculty of Science and Engineering

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