• Human brown adipose tissue activity assessed via positron emission tomography/computed tomography is inversely associated with environmental temperature

      Georgakopoulos, A; Koutsikos, J; Krase, A; Nintou, E; Metaxas, M; Athanasiou, K; Georgoulias, P; Gkiata, P; Koutedakis, Y; Dinas, P; et al. (Springer, 2018-10)
      Introduction: Cold exposure increases brown adipose tissue (BAT) activity, which may lead to increased resting energy expenditure (REE) with beneficial effects on body composition. However, evidence on the impact of normal daily living environmental temperature (Tenv) on BAT activity is limited. In this study, we examined the impact of Tenv on BAT activity of healthy men.
    • Circulating Sclerostin responses to acute weight and non weight bearing sport activity in pre adolescent males

      Jamurtas, Athanasios Z; Leontsini, Diamanda; Avloniti, Alexandra; Vlachopoulos, Dimitris; Stampoulis, Theodoros; Chatzinikolaou, Athanasios; Gracia-Marco, Luis; Ubago-Guisado, Esther; Makris, Konstantinos; Tournis, Symeon; et al. (Ovid Technologies (Wolters Kluwer Health), 2017-05-01)
      Mechanical loading, i.e. physical activity and/or exercise, promotes bone formation during growth. Sclerostin, a glycoprotein, mediates osteocytes' response to mechanical loading by inhibiting the Wnt/lf-catenin pathway thereby inhibiting bone formation.
    • Assessment of the relationship between macronutrient intake and browning of white fat in adult males

      Carrillo, Andres E; Dinas, Petros C; Valente, Angelica; Granzotto, Marnie; Rossato, Marco; Vettor, Roberto; Davies, Natalie A; Jamurtas, Athanasios Z; Koutedakis, Yiannis; Metsios, George S; et al. (Ovid Technologies (Wolters Kluwer Health), 2017-05-01)
      Research conducted in rodents and humans present conflicting results on the relationship between caloric intake and the browning of subcutaneous white adipose tissue (scWAT). For example, exercise combined with caloric restriction did not change browning indices measured from human scWAT samples. In another study, caloric restriction in mice resulted in the browning of both scWAT and visceral white adipose tissue. Few investigators, however, have examined the relationship between differences in macronutrient intake and browning processes of human scWAT.
    • Bone mineral density and body composition among athletes: Lightweight versus heavyweight sports

      van Santen, JA; Amorim, TA; Sanchez-Santos, MT; Newton, JL; Salbany, F; Pereira, C; Allen, N; Davies, MAM; Jackson, K; Koutedakis, Y; et al. (Springer, 2017-07-24)
      Objectives: Energy restriction and weight loss techniques are associated with adverse effects on bone mineral density (BMD) whilst participation in sports is known to be beneficial for skeletal health. However, it is not entirely clear the skeletal health status in lightweight sports where participants often use weight management techniques to attain relatively low mass. Therefore, the aim of this study is to evaluate the differences in BMD and body composition among athletes engaged in weight restricted and non-weight restricted sports.
    • The effect of pre-exercise ingestion of corinthian currant on endurance performance and blood redox status

      Deli, CK; Poulios, A; Georgakouli, K; Papanikolaou, K; Papoutsis, A; Selemekou, M; Karathanos, VT; Draganidis, D; Tsiokanos, A; Koutedakis, Y; et al. (Informa UK Limited, 2018-02-22)
      © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. The present study investigated the effect of Corinthian currant pre-exercise supplementation on metabolism, performance and blood redox status during, and after prolonged exercise. Eleven healthy participants (21-45y) performed a 90-min constant-intensity (60–70% VO2max) submaximal-trial, plus a time-trial (TT) to exhaustion (95% VO2max) after consuming an isocaloric (1.5g CHO/kg BM) amount of randomly assigned Corinthian currant or glucose-drink, or water (control). Blood was drawn at baseline, pre-exercise, 30min, 60min, 90min of submaximal-trial, post-TT, and 1h post-TT. Post-ingestion blood glucose (GLU) under Corinthian currant was higher compared with water, and similar compared with glucose-drink throughout the study. Respiratory quotient under Corinthian currant was similar with glucose-drink and higher than water throughout the submaximal trial. Accordingly, higher CHO and lower fat oxidation were observed under Corinthian currant compared with water. The TT performance was similar between Corinthian currant, glucose-drink and water. Redox status were similar under all three conditions. Reduced glutathione (GSH) declined while total antioxidant capacity (TAC) and uric acid increased during exercise. GSH and TAC returned to baseline, while uric acid remained increased the following 1h. Corinthian currant, although did not alter exercise-mediated redox status changes and performance, was equally effective to a glucose-drink in maintaining GLU levels during prolonged cycling.
    • Browning formation markers of subcutaneous adipose tissue in relation to resting energy expenditure, physical activity and diet in humans

      Dinas, PC; Valente, A; Granzotto, M; Rossato, M; Vettor, R; Zacharopoulou, A; Carrillo, AE; Davies, NA; Gkiata, P; Jamurtas, AZ; et al. (De Gruyter, 2017-07-05)
      © 2017 Walter de Gruyter GmbH, Berlin/Boston. Regular exercise and diet may contribute to white adipose tissue (WAT) conversion into a brown adipose-like phenotype that may increase resting energy expenditure (REE), leading to weight loss. We examined the relationship between REE, physical activity (PA) participation and diet with browning formation markers of subcutaneous WAT in healthy men. We assessed REE, diet and body composition of 32 healthy men [age (years): 36.06 ± 7.36, body mass index (BMI): 27.06 ± 4.62 (kg/m 2 )]. Participants also underwent measurements of PA [metabolic equivalent (MET)-min/week] using the International Physical Activity Questionnaire (IPAQ), while they undertook a subcutaneous fat biopsy from the abdominal region to assess the mRNA expressions of uncoupling protein 1 (UCP1), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), peroxisome proliferator-activated receptor alpha (PPARα) and peroxisome proliferator-activated receptor gamma (PPARγ). We found no associations between the UCP1, PGC-1α, PPARα and PPARγ mRNAs with REE, PA levels and diet (p > 0.05). However, the PGC-1α, PPARα and PPARγ mRNAs were more expressed in individuals displaying moderate rather than low PA levels (p < 0.05). Furthermore, PGC-1α, PPARα and PPARγ mRNAs were negatively correlated with fat mass percentage (p < 0.05). PGC-1α and PPARα mRNAs were also negatively correlated with BMI, while PGC-1α mRNA was inversely associated with waist-to-hip ratio (p < 0.05). REE, PA levels and diet are not associated with browning formation indices of subcutaneous adipose tissue in healthy adult men.
    • Validation of the Polar RS800CX for assessing heart rate variability during rest, moderate cycling and post-exercise recovery

      Tsitoglou, Kyriakos; Koutedakis, Yiannis; Dinas, Petros (F1000Research, 2018-09-20)
      Background: Heart rate variability (HRV) is an autonomic nervous system marker that provides reliable information for both disease prevention and diagnosis; it is also used in sport settings. We examined the validity of the Polar RS800CX heart rate monitor during rest, moderate cycling, and recovery in considering the total of 24 HRV indices. Method: A total of 32 healthy males (age=24.78±6.87 years, body mass index=24.48±3.13 kg/m 2 ) completed a session comprised by three 20-minute time periods of resting, cycling at 60% of maximal heart rate, and recovery using a Polar RS800CX and an electrocardiogram (ECG) monitors. The HRV indices included time-domain, frequency-domain, Poincaré plot and recurrence plot. Bland–Altman plot analysis was used to estimate agreement between Polar RS800CX and ECG. Results: We detected significant associations (r>0.75, p<0.05) in all HRV indices, while five out of 24 HRV indices displayed significant mean differences (p<0.05) between Polar RS800CX and ECG during the resting period. However, for the exercise and recovery periods, we found significant mean differences (p<0.05) in 16/24 and 22/24 HRV indices between the two monitors, respectively. Conclusion: It is concluded that Polar RS800CX is a valid tool for monitoring HRV in individuals at resting conditions, but it displays inconsistency when used during exercise at 60% of maximal heart rate and recovery periods.
    • The use of cardiopulmonary exercise testing in identifying the presence of obstructive sleep apnea syndrome in patients with compatible symptomatology

      Stavrou, V; Boutou, AK; Vavougios, GD; Pastaka, C; Gourgoulianis, KI; Koutedakis, Y; Daniil, Z; Karetsi, E; Laboratory of Cardiopulmonary Testing, Department of Respiratory Medicine, University of Thessaly, Larissa, Greece. Electronic address: vasileiosstavrou@hotmail.com. (Elsevier BV, 2019-01-23)
      © 2019 The aim of this study was to investigate the relationship between cardiopulmonary exercise testing (CPET) and the presence of obstructive sleep apnea syndrome (OSAS) in order to provide an innovative tool to identify patients with OSAS. A prospective nested case control design was adopted. A consecutive population of male volunteers referred to a Sleep Unit was subjected to nocturnal polysomnography, full lung function testing and maximal CPET. A stepwise linear discriminant function analysis (DFA) was applied to construct a model which could identify individuals with moderate-to-severe OSAS from healthy controls. The total of 30 volunteers formed the OSAS and 24 the non-OSAS groups. Demographic and somatometric parameters were similar between groups. Patients presented with lower Expiratory Reserve Volume (ERV: 106.7 ± 28.3 vs. 123.9 ± 22.1, p < 0.001), Leg Fatigue Borg scale (3.9 ± 1.1 vs. 6.1 ± 1.4, p < 0.001), VO 2peak (25.0 ± 5.9 vs. 32.9 ± 7.2 ml/kg −1 /min −1 , p < 0.001), peak breathing frequency (31.0 ± 5.8 vs. 35.5 ± 7.3 1/min −1 , p < 0.001) and peak heart rate (151.1 ± 17.7 vs. 171.2 ± 12.6 beats/min −1 , p < 0.001) compared to controls, but higher peak end-tidal CO 2 (P ET CO 2peak :38.6 ± 4.2 vs. 35.0 ± 4.9 mmHg, p = 0.043) and peak systolic (SBP:188.3 ± 21.9 vs. 173.1 ± 17.9 mmHg, p = 0.009) and diastolic (DBP: 91.3 ± 8.2 vs. 85.4 ± 8.2 mmHg, p = 0.011) blood pressure. Stepwise DFA indicated that ERV % of predicted (0.372), P ET CO 2peak (−0.376), SpO 2resting (0.0667), Leg Fatigue Borg scale (0.564), HR peak (0.530) and DBP peak (−0.543) could separate the two groups, with an overall predictive accuracy of 96.3%. Selected CPET parameters (ERV % of predicted , P ET CO 2peak , SpO 2resting , HR peak , DBP peak and Leg Fatigue Borg Scale ) are independently associated with OSAS presence and could discriminate patients with and without this disorder.
    • Evidence of blood and muscle redox status imbalance in experimentally induced renal insufficiency in a rabbit model

      Poulianiti, KP; Karioti, A; Kaltsatou, A; Mitrou, GI; Koutedakis, Y; Tepetes, K; Christodoulidis, G; Giakas, G; Maridaki, MD; Stefanidis, I; et al. (Hindawi Limited, 2019-04-04)
      Chronic kidney disease (CKD) is accompanied by a disturbed redox homeostasis, especially in end-stage patients, which is associated with pathological complications such as anemia, atherosclerosis, and muscle atrophy. However, limited evidence exists about redox disturbances before the end stage of CKD. Moreover, the available redox literature has not yet provided clear associations between circulating and tissue-specific (muscle) oxidative stress levels. The aim of the study was to evaluate commonly used redox status indices in the blood and in two different types of skeletal muscle (psoas, soleus) in the predialysis stages of CKD, using an animal model of renal insufficiency, and to investigate whether blood redox status indices could be reflecting the skeletal muscle redox status. Indices evaluated included reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione reductase (GR), catalase (CAT), total antioxidant capacity (TAC), protein carbonyls (PC), and thiobarbituric acid reactive substances (TBARS). Results showed that blood GSH was higher in the uremic group compared to the control (17.50 ± 1.73 vs. 12.43 ± 1.01, p = 0.033). In both muscle types, PC levels were higher in the uremic group compared to the control (psoas: 1.086 ± 0.294 vs. 0.596 ± 0.372, soleus: 2.52 ± 0.29 vs. 0.929 ± 0.41, p < 0.05). The soleus had higher levels of TBARS, PC, GSH, CAT, and GR and lower TAC compared to the psoas in both groups. No significant correlations in redox status indices between the blood and skeletal muscles were found. However, in the uremic group, significant correlations between the psoas and soleus muscles in PC, GSSG, and CAT levels emerged, not present in the control. Even in the early stages of CKD, a disturbance in redox homeostasis was observed, which seemed to be muscle type-specific, while blood levels of redox indices did not seem to reflect the intramuscular condition. The above results highlight the need for further research in order to identify the key mechanisms driving the onset and progression of oxidative stress and its detrimental effects on CKD patients.
    • The influence of Christian Orthodox thought on Stanislavski’s theatrical legacy

      Curpan, Gabriela (Informa UK Limited, 2019-08-01)
      Expressed through many Orthodox concepts, such as ‘soul’, ‘heart’, ‘love’, ‘beauty’ and ‘truth’, scattered throughout all his writings, Stanislavski’s personal religious feelings seemed constantly to have shaped his life-long sense of an artistic spirituality. Yet, in spite of this presence, the Orthodox connections appear to be neither properly analysed nor fully explained. Therefore, this paper strives to identify and reflect upon how such generally ignored but key Orthodox ideas might have had a crucial influence on shaping Stanislavski’s ‘system’.
    • Contemporary Czech Society by Lyons, Pat and Kindlerová, Rita (eds)

      Dickins, Tom (Modern Humanities Research Association, 2018-04)
      Contemporary Czech Society, edited by Pat Lyons and Rita Kindlerová, is a wide-ranging study of current attitudinal trends and changing realities, based on insights drawn largely from mass survey data. This highly engaging and thought-provoking work, which employs a social scientific framework, seeks and largely manages to present a value-free account of popular perceptions of the self and others. The publication comprises five sections: Preface; Introduction; Theory, methods, and structure; fifty-seven short empirically-informed chapters; and Conclusion, which contains a ‘cross-validation’. The separate chapters include contributions from eighteen different scholars, although Lyons’ own input merits special recognition, not least because it exceeds that of all the other authors as a whole. The main body of the text is divided into five broadly conceived thematic parts, which consider Czech society from economic, historical, political science, psychological, and sociological perspectives. Each chapter adopts an erotetic (question and answer) approach, and is grounded in solid scholarship, with reference to numerous secondary sources, and models and frameworks, but without conventional academic citations and footnotes. The study is thus presumably intended both for a general educated market keen to learn more about the dynamics and values Czech society, and for a more specialized readership, with an interest in particular aspects of the subject area.
    • London Road: the ‘irruption of the real’ and haunting utopias in the verbatim musical

      Zavros, Demetris; Rodosthenous, George (Routledge, 2017-08-15)
      The use of documentary material appeared in musical theatre at least as far back as Joan Littlewood's Oh! What a Lovely War, but it was not until London Road when the potential for a more experimental approach to the 'setting' of verbatim material was used in musical theatre. This chapter offers a slightly alternative perspective into the performance based on the belief that 'the reworking of speech into sung tunes' does not signal an absence as much as an 'irruption of the real' as discussed by Lehmann. It compares the stage and film versions of the musical in relation to their contiguity to the 'real' vs a utopian sensibility that accompanies the more traditionally escapist approaches to the film musical. The film audience becomes less able to viscerally and experientially appreciate the connection between the original and the aesthetic reconstitution that Lehmann so profoundly connects to the 'irruption of the real' in performance.
    • Selling a dream? Information asymmetry and integrity within promotional literature for popular music courses

      Hall, Richard (Intellect Books, 2019-07-01)
      Providers of higher education have a legal responsibility to provide accurate information to students. In an increasingly marketized sector, however, promotional imperatives place pressure on providers to ‘sell’ degrees to students. Given the indeterminate nature of popular music careers, not to mention the ‘intangible product’ that is Higher Education, the implicit or explicit indication of an assurance of career success upon completion of the degree could be regarded as being overstated. This article brings to bear a qualitative linguistic analysis of the terms and constructed meanings implied within promotional literature across a range of performance-based popular music degrees. It suggests that language in this context functions in a performative sense and can perpetuate questionable conceptions of popular music careers and the efficacy of degree courses. The article concludes with suggestions of improvements that might be made across the sector in the promotion of popular music degree courses.
    • Vilnius memoryscape: razing and raising of monuments, collective memory and national identity.

      Moore, Irina (John Benjamins Publishing, 2019-12-31)
      This article attempts to analyse collective memory formation (the study of monuments, memory, and public space) through the lens of semiotic landscape. A theoretical focus on power relations in “monumental politics” (Czepczyński, 2008; Forest, Johnson & Till, 2004; Gordon, 2001; Kaufman, 2001), the concept of memoryscape (Clack, 2011) and Van Gennep’s sociological concept of liminality (Van Gennep, A., 2004) and a methodological approach that “treats space as a discursive as well as physical formation” (Jaworski, A., Thurlow, C., 2010) are combined to examine the process of monument destruction, creation, and alteration in post-Soviet Vilnius.
    • Dialogism’s radical texts, and the death of the radical vanguard critic

      Geal, R; Cutchins, Dennis; Krebs, Katja; Voigts, Eckart (Routledge, 2018-04-01)
      © 2018 selection and editorial matter, Dennis Cutchins, Katja Krebs, Eckart Voigts; individual chapters, the contributors. It is not only artworks that can be grouped into historical and cultural contexts such as Sumerian or Anglo-Saxon epic poetry, Yoruba or Olmec statuary, Baroque chiaroscuro or Mughal miniature painting, Ming or Attic vases, the French nouvelle vague or Brazilian cinema novo. Academic interpretation of art, too, is located within historically specific networks of thought in which any one form of understanding art interacts in complex ways with prior and overlapping forms of understanding. This is true of all arts disciplines, but it has been particularly instrumental in relation to the study of adaptation. In part, this is no great revelation for the field. Because of certain consequences of its historical development, relating to the comparative valorisation of its intersecting media, adaptation studies has a strong record of historical self-analysis. The long domination of a fidelity-based model, which attempted to account for how filmmakers might ‘faithfully’ negotiate what Jack Jorgens calls the “expressive possibilities of shifting relations between words and images” (1977: 17), eventually ushered in a new theory which critiqued fidelity analysis by locating it within a historically specific context. But the precise form of the model which displaced fidelity analysis is not subject to the same historical explanation. That is not to say that its intellectual roots are not thought of historically. The new model is usually called dialogism because of the way that it principally draws on early twentieth-century Russian philosopher Mikhail Bakhtin’s (1981) idea that all works of art are constantly informed by and informing other works of art, so that adaptations are just more acute examples of this dialogue between texts. There are specific historical reasons, however, why it should be dialogism, rather than some other methodology which might make a similar criticism of fidelity analysis, that replaced fidelity as adaptation studies’ new orthodoxy at around the turn of this century.
    • The end of racism and the last ideology: The Cosby Show’s Fukuyaman neo-liberal children

      Geal, Robert; Schober, Adrian; Olson, Debbie (Routledge, 2018-06-26)
      Both popular and academic discourses on The Cosby Show have focused on the eponymous family’s post-racial representation. Challenging historically negative television and film depictions of the African American as an exotic and/or savage ‘Other’, the program’s upper middle-class professional family presented 1980s white America with an image of blackness that had been fully assimilated into hegemonic culture. Academic analyses of this acculturation have considered both the impact of this ostensibly positive depiction of the black family for white audiences, and the subtle traces of African American social and cultural experiences which appealed to black audiences. Discourses about the show’s children have also positioned the characters’ relationships with their white contemporaries within a post-racial context, so that they undergo the same kind of bildungsroman angst and trajectory as other, whiter, 1980s coming-of-age narratives, without any particular experience rooted in racial difference. This essay situates the show’s children within a wider post-racial context that dominated American political and social culture during the period 1984-1992 when the show ran. This was the era of triumphant Reaganomics, punctuated by the fall of the Berlin Wall, and bookended with Francis Fukuyama’s influential panegyric to neo-liberalism’s victory over every other possible form of ideology, The End of History and the Last Man. The Cosby Show’s professional American nuclear family is post-racial not only because of the gradual impact of socio-cultural and legal developments emanating from the Civil Rights movement. Even more fundamentally, the enormous popularity of the show’s Huxtable family, amongst both black and white audiences, in America and beyond, encapsulates Fukuyama’s color-blind ideological model – a celebration of hard work and cooperation leading to the enjoyable consumption of plenty, with any inconvenient impediments to this vision, such as race, class, gender or sexuality, overcome through virtuous labor and consumption. The show’s children, inheritors of the End of History, are the central drivers and beneficiaries of this process.
    • The Demise of the cinematic zombie: from the golden age of Hollywood to the 1940s

      Fenton, Louise; Degiglio-Bellemare, Mario; Ellbé, Charlie; Woofter, Kristopher (Lexington Books, 2014-12-11)
      The 1940s is a lost decade in horror cinema, undervalued and written out of most horror scholarship. This collection revises, reframes, and deconstructs persistent critical binaries that have been put in place by scholarly discourse to label 1940s horror as somehow inferior to a “classical” period or “canonical” mode of horror in the 1930s, especially as represented by the monster films of Universal Studios. The book's four sections re-evaluate the historical, political, economic, and cultural factors informing 1940s horror cinema to introduce new theoretical frameworks and to open up space for scholarly discussion of 1940s horror genre hybridity, periodization, and aesthetics. Chapters focused on Gothic and Grand Guignol traditions operating in forties horror cinema, 1940s proto-slasher films, the independent horrors of the Poverty Row studios, and critical reevaluations of neglected hybrid films such as The Vampire’s Ghost (1945) and “slippery” auteurs such as Robert Siodmak and Sam Neufield, work to recover a decade of horror that has been framed as having fallen victim to repetition, exhaustion, and decline.
    • The Ends of Art (curated by Euripides Altintzoglou)

      Altintzoglou, Euripides; Altintzoglou, Euripides; Abernethy, Jim; Bracey, Andrew; Cornford & Cross; Kelland, Dean; Kossoff, Adam; Timberlake, John; Payne, Alistair; Dalgleish, Mat (2013-07-05)
      From Marius de Zayas to David Rabinowitch Richard Huelsenbeck and, and from Arthur Danto to David Kuspit art is declared dead every time it goes through a critical stage in its course of development. Post-modern stylistic plurality posed as the end of art history but recently relational aesthetics placed Pluralism under dispute and in doing so signaled the dawn of a new era. Instead of joining conservative historians in a post-apocalyptic religiosity about the loss of all that was great in art we need to turn to critical self-reflective strategies that echo the spirit of conceptualism. The intention of this group of works is not to simply demonstrate ways by which there can be art after the ‘end of art’ and thus to seek for means to satisfy Arthur Danto’s uncertainty about the future of art after Plurality by sustaining a purist approach to art history. Rather, each work included in the Ends of Art deals solely with the nature of a given discipline through another and, thus investigates the potential for an even more radical and thorough process of examination of the changing nature of art through interdisciplinarity; expanding the field of each discipline is the methodology of this exhibition, not the aim. At the core of this methodology is the intention to eradicate the last remaining traces of humanism in art history: the dissolution of distinct art disciplines for the means of theoretical analysis.
    • The critical invariant: Avant-garde and change

      Altintzoglou, Evripidis (Intellect, 2018-12-01)
      ‘Change’ is the locus of the avant-garde’s revolutionary character. Historical claims and contemporary theorizations of the avant-garde enforce methodological distinctions between radical and conforming attitudes that fluctuate according to existing political agendas. This process of instrumentalization renders the avantgarde susceptible to the conformity of institutionalization. More importantly it prescribes the avant-garde with a subservient role that controls its operational means and deflates its capacity to produce politics. What is to be done, if the avant-garde achieves its goal for socio-political change? Are we to abandon the spirit of critical reflection and surrender to the conditions of the next system? How can there be an avant-garde after capitalism if its ends are solely confined in the substitution of one system with another? This article traces out this problem, assessing what kind of emancipatory potential we might expect, or hope for, from a post-capitalist avant-garde, by advancing a critical examination of recent theories of political subjectivity, the dialectics of change and the reconciliation of the institution.
    • Feeling the beat where it counts: fostering multi-limb rhythm skills with the haptic drum kit

      Holland, SImon; Bouwer, Anders J; Dalgelish, Mathew; Hurtig, Topi M (ACM Press, 2010)
      This paper introduces a tool known as the Haptic Drum Kit, which employs four computer-controlled vibrotactile devices, one attached to each wrist and ankle. In the applications discussed here, haptic pulses are used to guide the playing, on a drum kit, of rhythmic patterns that require multi-limb co-ordination. The immediate aim is to foster rhythm skills and multi-limb coordination. A broader aim is to systematically develop skills in recognizing, identifying, memorizing, retaining, analyzing, reproducing, and composing polyphonic rhythms. We consider the implications of three different theories for this approach: the work of the music educator Dalcroze (1865-1950 [1]; the entrainment theory of human rhythm perception and production [2,3]; and sensory motor contingency theory [4]. In this paper we report on a design study; and identify and discuss a variety of emerging design issues. The study demonstrates that beginning drummers are able to learn intricate drum patterns from haptic stimuli alone.