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Assessment of the relationship between macronutrient intake and browning of white fat in adult malesCarrillo, Andres E; Dinas, Petros C; Valente, Angelica; Granzotto, Marnie; Rossato, Marco; Vettor, Roberto; Davies, Natalie A; Jamurtas, Athanasios Z; Koutedakis, Yiannis; Metsios, George S; et al. (Ovid Technologies (Wolters Kluwer Health), 2017-05-01)Research conducted in rodents and humans present conflicting results on the relationship between caloric intake and the browning of subcutaneous white adipose tissue (scWAT). For example, exercise combined with caloric restriction did not change browning indices measured from human scWAT samples. In another study, caloric restriction in mice resulted in the browning of both scWAT and visceral white adipose tissue. Few investigators, however, have examined the relationship between differences in macronutrient intake and browning processes of human scWAT.