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The possible association of female pattern hair loss and alteration in serum cholecalciferol levelBackground: Vitamin D has a central role in neuronal, reproductive, autoimmune, infectious, and heart diseases. Female Pattern Hair Loss (FPHL) is described as a non-scarring, progressive thinning of the hair resulting from a decreasing ratio of terminal hairs to thinner vellus hairs. Aim: To explore the possibility of vitamin D deficiency contribution to hair loss in women in the local population in West Midlands England. Method: Records of women from different age groups who were treated in the dermatology outpatient clinic for any skin conditions and had their vitamin D status assessed as part of their usual care. In this study we also examine the impact of vitamin D levels and age on hair loss. Results: The studies reviewed medical records of 48 patients diagnosed with dermatological conditions. Low levels of vitamin D significantly affects the loss of hair (p = 0.046). The odds ratio estimated is 3.545. Our results show that the impact of low vitamin D level is significantly prevalent for the age groups 35 - 45 and moderately impacted age group 55 - 65 years. Conclusion: Vitamin D has a significant role in hair-loss process, and possibly early correction may have a role in prevention and treatment in women aged 35 - 45 year of age. .