There has been a good effort made in Abu Dhabi for the last couple of years between government stakeholders to develop a road safety strategy, define rules and responsibilities, and gain a fully coordinated and integrated framework to deal with road safety. According to my point of view, the challenges that might be seen as a problem for the future development of Abu Dhabi can be the management and the usage of traffic safety technologies to reduce serious road traffic accidents. This study focused on the relationship between the use of traffic safety technologies and serious road traffic accidents on Abu Dhabi Highways. The motivation for this research is to implement correctly the traffic safety technologies in Abu Dhabi highways as a part of the need to adopt plans, programmes, and preventive measures to reduce or prevent the occurrence of traffic accidents in order to ensure the safety of individuals and property, in addition to preserving the security of the state and its human and economic components. The overall approach to this study is a mixed methodology, which combines quantitative and qualitative methods. A questionnaire is one method used in this regard, and is designed to be quantitative. In the quantitative method, comparing statistics of fatalities and injuries before and after installation of the speed cameras is used. As a result of this study and by making the connectivity between reviewing the results and findings of the literature review, identifying the questionnaire results, and exploring the before and after statistics led to findings which were used to develop a decision support framework that can be used to advise the regional safety strategy to be sustainable. The design framework was also validated through Abu Dhabi highways by a panel of experts, which was carried out using the focus group method, which was qualitative in nature. It is recommended from this research to invest much in traffic safety technologies, focus more on driver support systems and rapid response systems, improve driver behaviour as a priority in Abu Dhabi highways using traffic safety technologies, and integrate the compatibility of all of the above through an integrated system and specific performance indicators that are measured and followed up on an ongoing basis, and supported by geographic information systems (GIS).