Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Authors
Nelson, Paul N.Carnegie, P.R.
Martin, Jan H.
Ejtehadi, H. Davari
Hooley, Paul
Roden, Denise A.
Rowland-Jones, S.
Warren, Phil
Astley, S.J.
Murray, Paul G.
Issue Date
2003
Metadata
Show full item recordAbstract
Human endogenous retroviruses (HERVs) are a family of viruses within our genome with similarities to present day exogenous retroviruses. HERVs have been inherited by successive generations and it is possible that some have conferred biological benefits. However, several HERVs have been implicated in certain cancers and autoimmune diseases. This article demystifies these retroviruses by providing an insight into HERVs, their means of classification, and a synopsis of HERVs implicated in cancer and autoimmunity. Furthermore, the biological roles of HERVs are explored.Citation
Journal of Clinical Pathology: Molecular Pathology, 56 (1): 11-18Publisher
BMJ PublishingJournal
Journal of Clinical Pathology: Molecular PathologyPubMed ID
12560456Additional Links
http://mp.bmj.com/cgi/content/full/56/1/11Type
Journal articleLanguage
enISSN
1366-8714Collections
Related articles
- Human endogenous retroviruses: transposable elements with potential?
- Authors: Nelson PN, Hooley P, Roden D, Davari Ejtehadi H, Rylance P, Warren P, Martin J, Murray PG, Molecular Immunology Research Group.
- Issue date: 2004 Oct
- Implication of human endogenous retroviruses in the development of autoimmune diseases.
- Authors: Balada E, Vilardell-Tarrés M, Ordi-Ros J
- Issue date: 2010 Aug
- Insertional polymorphisms: a new lease of life for endogenous retroviruses in human disease.
- Authors: Moyes D, Griffiths DJ, Venables PJ
- Issue date: 2007 Jul
- Utility of next-generation RNA-sequencing in identifying chimeric transcription involving human endogenous retroviruses.
- Authors: Sokol M, Jessen KM, Pedersen FS
- Issue date: 2016 Jan-Feb
- Role of endogenous retroviruses in autoimmune diseases.
- Authors: Colmegna I, Garry RF
- Issue date: 2006 Dec