A brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
AuthorsMetsios, Giorgos S.
Flouris, Andreas D.
Jamurtas, Athanasios Z.
MetadataShow full item record
AbstractCONTEXT: Active smoking influences normal metabolic status and thyroid function. OBJECTIVE: The objective was to assess experimentally the effects of 1 h of moderate passive smoking in a controlled simulated bar/restaurant environment on the metabolism and thyroid hormone levels in healthy nonsmokers. PARTICIPANTS: Eighteen (nine females, nine males) healthy individuals (mean +/- sd: age, 25.3 +/- 3.1 yr; height, 174.0 +/- 10.1 cm; weight, 65.2 +/- 13.7 kg) participated in the study. DESIGN: In repeated-measures randomized blocks, participants visited the laboratory on 2 consecutive days. In the experimental condition, they were exposed to 1 h of moderate passive smoking at a carbon monoxide concentration of 23 +/- 1 ppm in an environmental chamber, whereas in the control condition participants remained in the same chamber for 1 h breathing normal atmospheric air. MAIN OUTCOME MEASURES: In both conditions, cotinine serum and urine levels, resting energy expenditure (REE), as well as concentration of T3, free T4, and TSH were assessed before participants entered the chamber and immediately after their exit. Heart rate and blood pressure were tested in 10-min intervals during all REE assessments. RESULTS: The mean +/- sd difference of serum and urine cotinine levels (-0.27 +/- 3.94 vs. 14.01 +/- 6.54 and 0.05 +/- 2.07 vs. 7.23 +/- 3.75, respectively), REE (6.73 +/- 98.06 vs. 80.58 +/- 120.91) as well as T3 and free T4 (0.05 +/- 0.11 vs. 0.13 +/- 0.12 and 0.02 +/- 0.15 vs. 0.22 +/- 0.20) were increased in the experimental compared with the control condition at baseline and follow-up (P < 0.05). No statistically significant variation was observed in the mean difference of the remaining parameters (P > 0.05). Serum and urine cotinine values were linearly associated with REE (P < 0.05). CONCLUSION: One hour of passive smoking at bar/restaurant levels is accompanied by significant increases in metabolism and thyroid hormone levels.
CitationThe Journal of Clinical Endocrinology and Metabolism, 92 (1): 208-11
PublisherThe Endocrine Society/HighWire Press
JournalThe Journal of Clinical Endocrinology and Metabolism
- Thyroid hormone levels associated with active and passive cigarette smoking.
- Authors: Soldin OP, Goughenour BE, Gilbert SZ, Landy HJ, Soldin SJ
- Issue date: 2009 Aug
- Sexual dimorphism in the acute effects of secondhand smoke on thyroid hormone secretion, inflammatory markers and vascular function.
- Authors: Flouris AD, Metsios GS, Jamurtas AZ, Koutedakis Y
- Issue date: 2008 Feb
- Changes in thyroid hormone metabolism in exertional heat stroke with or without acute renal failure.
- Authors: Chen WL, Huang WS, Lin YF, Shieh SD
- Issue date: 1996 Feb
- Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function.
- Authors: Flouris AD, Chorti MS, Poulianiti KP, Jamurtas AZ, Kostikas K, Tzatzarakis MN, Wallace Hayes A, Tsatsakis AM, Koutedakis Y
- Issue date: 2013 Feb
- Growth hormone administration stimulates energy expenditure and extrathyroidal conversion of thyroxine to triiodothyronine in a dose-dependent manner and suppresses circadian thyrotrophin levels: studies in GH-deficient adults.
- Authors: Jørgensen JO, Møller J, Laursen T, Orskov H, Christiansen JS, Weeke J
- Issue date: 1994 Nov