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    Bacterial synthesis of biodegradable polyhydroxyalkanoates.

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    Authors
    Verlinden, Rob A. J.
    Hill, David J.
    Kenward, M.A.
    Williams, Craig D.
    Radecka, Izabela
    Issue Date
    2007
    
    Metadata
    Show full item record
    Abstract
    Various bacterial species accumulate intracellular polyhydroxyalkanoates (PHAs) granules as energy and carbon reserves inside their cells. PHAs are biodegradable, environmentally friendly and biocompatible thermoplastics. Varying in toughness and flexibility, depending on their formulation, they can be used in various ways similar to many nonbiodegradable petrochemical plastics currently in use. They can be used either in pure form or as additives to oil-derived plastics such as polyethylene. However, these bioplastics are currently far more expensive than petrochemically based plastics and are therefore used mostly in applications that conventional plastics cannot perform, such as medical applications. PHAs are immunologically inert and are only slowly degraded in human tissue, which means they can be used as devices inside the body. Recent research has focused on the use of alternative substrates, novel extraction methods, genetically enhanced species and mixed cultures with a view to make PHAs more commercially attractive.
    Citation
    Journal of Applied Microbiology, 102(6): 1437-1449
    Publisher
    Wiley InterScience
    URI
    http://hdl.handle.net/2436/20392
    DOI
    10.1111/j.1365-2672.2007.03335.x
    PubMed ID
    17578408
    Additional Links
    http://www3.interscience.wiley.com/journal/118490442/abstract
    Type
    Journal article
    Language
    en
    ISSN
    1364-5072
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1365-2672.2007.03335.x
    Scopus Count
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    Faculty of Science and Engineering

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